ecstasy is one of the newest drugs in the same category with amphetamines which has stimulating effects in the same families of amphetamines and lsd. there hasn't been a structured and organized study on this drug in iran. it has been used in great scale in all western countries. studies at san francisco and australia with snowballing method, revealed that this drug is used by active young...

Ecstasy (MDMA, 3,4-methylendioxymethamphetamine) and the stimulants methamphetamine (METH, speed) and amphetamine are popular drugs among young people, particularly in the dance scene. When given in high doses both MDMA and the stimulant amphetamines are clearly neurotoxic in laboratory animals. MDMA causes selective and persistent lesions of central serotonergic nerve terminals, whereas amphet...

In recent years, besides the classic designer drugs of the amphetamine type, a series of new drug classes appeared on the illicit drugs market. The chemistry, pharmacology, toxicology, metabolism, and toxicokinetics is discussed of 2,5-dimethoxy amphetamines, 2,5-dimethoxy phenethylamines, beta-keto-amphetamines, phencyclidine derivatives as well as of herbal drugs, ie, Kratom. They have gained...

We describe a method for determination of barbiturates, amphetamines, opiates, and methadone by the “enzyme multiplied immunoassay technique” (EMIT) applied to the centrifugal analyzer. This method gives results that agree well (92% for barbiturates, 97% for opiates, 94% for methadone, and 96% for amphetamines) with those obtained by the same technique with the SyvaGilford EMIT instrumentation,...

In an attempt to relate the hallucinogenic potencies in man of some biologically important amphetamines and phenethylamines, the 1-octanol-water partition coefficients for 11 amphetamines were determined. Using these values and published Hansch pi constants, the log P for 17 additional amines was estimated. It was found that lipophilicity, as measured by the log of the partition coefficient, ma...

Volume 86, Number 5 www.aafp.org/afp American Family Physician 413 Clinical Scenario A 36-year-old man who is enrolled in a master’s degree program presents to your office stating that he is having difficulty focusing and concentrating on class material, and is afraid he will not be able to graduate. He reports a history of attention-deficit/ hyperactivity disorder (ADHD) that was successfully ...