Anabolic steroid abuse in athletes has been associated with a wide range of adverse conditions, including hypogonadism, testicular atrophy, impaired spermatogenesis, gynaecomastia, and psychiatric disturbance. But what effect does steroid abuse have on the cardiovascular system?

The synthetic anabolic steroids have structural features which distinguish them from the natural steroid hormones. It should therefore be possible to detect the taking of these substances by testing for their presence in either blood or urine. At present suitable techniques include gas chromatography, mass spectrometry and radioimmunoassay. For practical and psychological reasons urine tests ar...

To determine the rate of current or previous use of anabolic steroids by students at a UK college of technology, a questionnaire survey of 687 day students was conducted. The questionnaire began with a general section for all of the students, which ended with the question 'Have you ever used anabolic steroids?'. A further section specifically for anabolic steroid users examined patterns of use,...

OBJECTIVE To determine the characteristics of female US high school students reporting anabolic steroid use. DESIGN Cross-sectional assessment using the 2003 Centers for Disease Control and Prevention national school-based Youth Risk Behavior Survey database. SETTING Nationally representative sample of US high schools. PARTICIPANTS Female students in grades 9 through 12 (n = 7544). MAIN...

1. A method is described for the routine isolation of ribosomes from small quantities of skeletal muscle that have been homogenized with the Ultra-Turrax tissue disintegrator. 2. Ribosomes prepared by this method from rats receiving triamcinolone acetonide or rabbits receiving cortisone acetate show a marked fall in their ability to incorporate amino acids when compared with ribosomes from cont...

Anabolic steroid abuse has been associated with thrombosis and arteriosclerosis, both of which predispose to myocardial ischemia and infarction. However, there are reports of sudden cardiac death in the absence of thrombus and atheroma following anabolic steroid use. Although treatment with the commonly abused steroid, nandrolone, has been shown to decrease recovery of systolic function followi...

Discussion of the problem of anabolic-androgenic steroid abuse has been generally limited to the context of professional sports and major international sporting events such as the Olympics. Anabolic-androgenic steroid abuse is not, however, limited to professional and 61ite athletes, nor to athletes only, but it has now spread to amateur and lower level athletes as well as to the general public...