This study was undertaken to investigate the effects of chronic administration of chloroform extract of Andrographis paniculata, known to possess some cardioprotective action, on endothelial dysfunction using isolated spontaneously hypertensive (SH) rat thoracic aorta. Verapamil hydrochloride was used as a positive control to compare its effect on endothelial dysfunction to that of Andrographis...

Andrographis paniculata nees (Acanthaceae) is a medicinal plant traditionally used for the treatment of anti-inflammatory, antibacterial, antioxidant, antiparasitic, antispasmodic, antidiabatic, anti carcinogenic, antipyretic, antidiarrhoeal, hepatoprotective, nematocidal, antiHIV and several infectious diseases ranging from malaria to dysentery. The plant is widely used in ayurvedic and homeop...

Penelitian ini bertujuan untuk mengetahui total leukosit dan diferensial ayam kampung (Gallus gallus domesticus) dengan pemberian ekstrak sambiloto (Andrographis paniculata). dilaksanakan pada Januari--Maret 2022 di unit kandang Laboratorium Lapang Terpadu, Fakultas Pertanian, Universitas Lampung. Pemeriksaan sampel darah dilakukan Patologi Klinik, Kedokteran Hewan, Gadjah Mada. menggunakan 4 p...

Present study evaluated the cardioprotective effect of Andrographis paniculata (100, 200 or 400 mg/kg) against isoproterenol (85 mg/kg, b.w.)-induced cardiotoxicity referred as myocardial infarction in rats. Isoproterenol significantly (p < 0.05) decreased mean arterial pressure, heart rate, contractility and relaxation and increased left ventricular end diastolic pressure. Isoproterenol also s...

The efficacy of Andrographis paniculata (AP) extract was studied on atrazine induced hepatic damage in rats. Ethanolic extract of AP (150mg/kg body weight) was found to protect the male wistar rats from hepato toxic action of atrazine as evidence by significant reduction in the level of lipid peroxidation and increased the antioxidant defense system activity in the atrazine intoxicated rats. Ho...

Herbal utilization, as an antidiabetes agent, is interesting topic to find acceptable herbal drugs decrease blood glucose levels. The aim of this review evaluate the potency selected medicines reduce levels and identify chemical compounds responsible for reducing glucose. mechanisms action different used might be also different. reduction by Aloe vera, Andrographis paniculata, Trigonella foenum...

Andrographis paniculata (Sambiloto) adalah anggota famili Acanthaceae yang memproduksi beragam metabolit sekunder dan berpotensi sebagai senyawa antioksidan. Disamping dari tumbuhan alaminya, antioksidan A. juga dapat diperoleh melalui jamur berkolonisasi di dalam jaringannya. Penelitian ini bertujuan untuk menganalisis sifat komponen fitokimia pada endofitik BS-1 jaringan bunga menggunakan ber...

Andrographis paniculata (Burm.f.) Nees (Acanthaceae), a plant widely used as traditional herbal medicine in many countries, has drawn attention of the researchers in recent years. Its major constituents are diterpenoids and flavonoids. This article reviews the anti-hepatotoxic effects of A. paniculata extract and derivative compounds, such as andrographolide, the major active compound, most stu...

Andrographis paniculata Nees.,a member of the family Acanthaceae is a plant commonly used by the local people, for the treatment of common cold, liver diseases, snake bite and some skin infection. The aerial part of the plant was screened for their phytochemical properties and antimicrobial activity. Antimicrobial activity of leaf extract of Andrographis paniculata, was studied using different ...