Although the utility and benefits of anesthesia and analgesia are irrefutable, their practice is not void of risks. Almost all drugs that produce anesthesia endanger cardiovascular stability by producing dose-dependent impairment of cardiac function, vascular reactivity, and compensatory autoregulatory responses. Whereas anesthesia-related depression of cardiac performance and arterial vasodila...

Dexmedetomidine and ketamine infusions were the main anesthetic for a 15-year-old girl, who underwent scoliosis repair surgery with intraoperative wake-up test, somatosensory evoked potential (SSEP), and motor-evoked potential (MEP) monitoring. To achieve maintenance of anesthesia, dexmedetomidine and ketamine were administered concomitantly. The dexmedetomidine dose ranged from 0.9 to 1.2 micr...

Continuous monitoring of the anesthetic drug dosage administered during a surgery is very important to avoid the patient's interoperative awareness due to inadequate levels of anesthesia. The traditional methods of assessing the anesthetic depth levels which are based on the qualitative physical signs such as heart rate, blood pressure, pupil size, sweating, etc are not very accurate as these a...

Anesthetic agents cause unique electroencephalogram (EEG) activity resulting from actions on their diverse molecular targets. Typically to produce balanced anesthesia in the clinical setting, several anesthetic and adjuvant are combined. This creates challenges for use of intraoperative EEG monitoring, because computational approaches mostly limited spectral analyses different combinations resp...

Purpose of the study: based on analysis bispectral index (BIS-index), to assess adequacy depth anesthesia in patients with oncological profile. Material and methods. An BIS-monitoring was carried out during 77 surgical interventions oncosurgical profile Grodno University Clinic. Results. 30 minutes after start surgery, a decrease concentration Sevorane inhaled mixture 0.8-0.6 vol% lead signific...