نتایج جستجو برای: angiotensin ii receptors
تعداد نتایج: 812381 فیلتر نتایج به سال:
AIM Angiotensin II is well known for its contractile effects on smooth muscle cells. This effect is also present in the gut previously shown in animal models. The aim of this study was to clarify expression and localization of angiotensin II receptors in the human small intestine and to explore the pharmacological profile of angiotensin II effects in vitro. METHODS Strips of jejunal muscle wa...
Angiotensin II and endothelin-1 activate their respective AT(1) and ET(A) receptors on vascular smooth muscle cells, producing vasoconstriction, and both peptides are implicated in the pathogenesis of essential hypertension. Angiotensin II potentiates the production of endothelin, and conversely endothelin augments the synthesis of angiotensin II. Both AT(1) and ET(A) receptor antagonists lower...
there are controversial reports about the effect of captopril on pain modulation. also while captopril may potentiate morphine analgesia, enalapril has not such an effect and interaction of morphine with angiotensin ii receptor antagonists and other angiotensin converting enzyme inhibitors has not been studied yet. therefore, this study was designed to assess the effect of captopril, lisinopril...
Background: Hypertension during pregnancy period along with the presence of protein in the urine, after the 20th weeks of gestation is called preeclampsia (PE). About five percent of all pregnancies are manifested with PE and its exact etiology has still remained unknown. The renin-angiotensin system (RAS) has an important role in the regulation of blood pressure during pregnancy and so pathoph...
OBJECTIVE Angiotensin II is recognized as one of the major mediators of cardiovascular pathology. Because connective tissue growth factor (CTGF) is involved in the pathophysiologic processes underlying fibrotic diseases, its regulation by angiotensin II was investigated. METHODS AND RESULTS In the 2-kidney, 1-clip model of renovascular hypertension, increased expression of CTGF was detectable...
Radford published an interesting clinical case report of rural patients taking angiotensin II type 1 (AT1) receptor antagonist – commonly also referred to as angiotensin receptor antagonists, AT1 receptor blockers, angiotensin receptor blockers or ARBs – who experienced a sudden loss of consciousness whilst exercising gently in the heat. The findings in this manuscript support, in a clinical se...
Angiotensin II, the effector peptide of the renin-angiotensin system, regulates cellular growth in response to developmental, physiological, and pathological processes. The identification of renin-angiotensin system components and angiotensin II receptors in cardiac tissue suggests the existence of an autocrine/paracrine system that has effects independent of angiotensin II derived from the cir...
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