The skull base surgery is one of the most demanding surgeries. There are different structures that can be injured easily, by operating in the skull base. It is very important for the neurosurgeon to choose the right approach in order to reach the lesion without harming the other intact structures. Due to the pioneering work of Cushing, Hirsch, Yasargil, Krause, Dandy and other dedicated neurosu...

Reconstruction of the anterior skull base is one of the greatest challenges for reconstructive surgeons. Sometimes, the defect is so large that a local flap is insufficient for the reconstruction. In this report, we present a case of malignant meningioma of the anterior skull base. The tumor was treated by surgical excision resulting in a large defect from the anterior skull base to the nasal c...

A 42-year-old woman presented with symptoms of left-sided nasal obstruction, cerebrospinal fluid (CSF) rhinorrhea, and frequent sinus infections. Radiologic investigation revealed a tumor destructing the left cribriform plate and forming opacifications in the olfactory area. She had left-sided submucosal meningocele, deviating the septum to the right side. Intracranial involvement was not obser...

BACKGROUND Here, we introduced our short experience on the application of a new CUSA Excel ultrasonic aspiration system, which was provided by Integra Lifesciences corporation, in skull base meningiomas resection. METHODS Ten patients with anterior, middle skull base and sphenoid ridge meningioma were operated using the CUSA Excel ultrasonic aspiration system at the Neurosurgery Department of...

Different reconstruction techniques of the anterior and middle skull base as consequence of a defect after surgical treatment of neoplastic pathologies are described in the literature. The aim of the present study is to present our experience regarding the use of microvascular free flaps for reconstruction of the anterior or middle skull base after large defects caused by removal of malignant n...

OBJECTIVES/HYPOTHESIS To conceive and critically evaluate an adaptation of the split calvarial osteopericranial flap for reconstruction following endoscopic endonasal resection of the anterior skull base. STUDY DESIGN Cadaveric anatomic study. METHODS Five cadavers were embalmed with methanol, and vasculature was injected with latex. Endoscopic endonasal resection of the anterior skull base...

introduction: skull-based osteomyelitis is bony infection which generally originates from inadequately treated chronic infection, adjoining tissue infection or after trauma.case: 11 month female child had a trivial fall while standing near a bucket. the child developed fracture of right clavicle and left orbital swelling which was inadequately treated. this resulted in in spread of infection to...

localization of brain lesions and prevention of damage to vital structures are important in operation of brain pathologies. despite development of many techniques including angiography, mri, sonography, and frame base stereotaxy, a more accurate localizing technique is still needed (1, 2). a step forward to achieve this goal is to develop a navigation system. in this manuscript, we explained so...

OBJECTIVE To present our method for anterior skull base reconstruction after oncological resections. METHODS One hundred nine patients who had undergone 120 anterior skull base resections of tumors (52 malignant [43%], 68 benign [57%]) via the subcranial approach were studied. Limited dural defects were closed primarily or reconstructed using a temporalis fascia. Large anterior skull base def...