BACKGROUND Disseminated leishmaniasis is an emerging infectious disease, mostly due to L. braziliensis, which has clinical and histopathological features distinct from cutaneous leishmaniasis. METHODS In the current study we evaluated the in vitro production of the cytokines IFN-gamma, TNF-alpha, IL-5 and IL-10 by peripheral blood mononuclear cells (PBMC) from 15 disseminated leishmaniasis an...

Leishmaniasis is a complex disease caused by more than 20 species of the Leishmania parasite, with over a million new cases occurring every year.(1) It breaks out in foci across tropical and temperate regions around the world, in areas where the sandfly, responsible for its transmission, lives. In anthroponotic leishmaniasis (transmission between humans by the sandfly) humans are the only reser...

Background and Aims: Leishmaniasis is an intracellular protozoan- parasitic disease, the common vector of transmission. Both zoonotic and anthroponotic cutaneous leishmaniasis (CL) are endemic in different foci. With regard to the cutaneous form, 1.0-1.5 million cases were reported annually with 90% of the cases. Although antimony-containing compounds that are the main drugs used to treat Leish...

Cutaneous leishmaniasis is rare in Nepal although visceral leishmaniasis (kala azar) is common in the Terai region. In country like ours where tuberculosis is more prevalent cutaneous leishmaniasis is very likely to be mistreated as cutaneous tuberculosis, especially lupus vulgaris. Here we report a series of four cases of cutaneous leishmaniasis who presented in the out patient department at T...

Both cutaneous and mucocutaneous leishmaniasis are endemic in Northern Ethiopia. The different clinical presentations depend on the responsible organism and the host's immune response. Localized cutaneous leishmaniasis is the type most frequently seen. Diffuse cutaneous leishmaniasis is relatively rare and usually associated with mucous membrane involvement. Diffuse cutaneous leishmaniasis pres...

Cutaneous leishmaniasis is caused by different species of the Leishmania genus. Leishmania(Leishmania) infantum, causing cutaneous leishmaniasis, has been described in patients living in areas where visceral leishmaniasis is endemic. In this study, it was possible to characterize this species in seven slides from cutaneous tissue imprints from patients with cutaneous leishmaniasis in the State ...

Dear Editor, We would like to discuss on the report on “Zosteriform cutaneous leishmaniasis” [1] Ramot et al. reported that “dermoscopy has proven to be an accessible and easy tool to diagnose such atypical presentation of cutaneous leishmaniasis, and dermatologists in endemic areas should be familiar with its typical dermoscopic features” [1]. In fact, cutaneous leishmaniasis is an important t...

background: leishmaniasis is a sand fly-borne disease caused by the protozoan parasites belonging to the genus leishmania . because of the preventing and controlling methods, clinical course, prognosis and choice of treatment are differing from species; differentiation of species is critical. the present study was aimed to detect the parasite species using the pcr-rflp method. methods: a total ...