http://www.fda.gov/Drugs/DrugSafety/ucm365050.htm FDA Drug Safety Communication: FDA requires label changes to warn of risk for possibly permanent nerve damage from antibacterial fluoroquinolone drugs taken by mouth or by injection (8/15/13 update). “The U.S. Food and Drug Administration (FDA) has required the drug labels and Medication Guides for all fluoroquinolone antibacterial drugs be upda...

The antibacterial activity of cefminox (CMNX) against anaerobic bacteria was studied in vitro. The results are as follows: 1. CMNX exerted antibacterial activity against a wide range of anaerobes, excluding Clostridium innocuum. The antibacterial activity of CMNX against Bacteroides fragilis was comparable to that of latamoxef and superior to cefoxitin, but CMNX's activity against anaerobic coc...

objective: the study was conducted to investigate the antibacterial and anthelmintic activities and to determine total phenolic contents of methanolic extract of piper betel leaves. materials and methods: the extract was subjected to assay for antibacterial activity using both gram positive and gram negative bacterial strains through disc diffusion method; anthelmintic activity with the determi...

The alcoholic and aqueous extracts of five medicinal plants (Cassia fistula, Albizia lebbeck, Cassia occidentalis , Sphaeranthus indicus and Vitex nigundo) collected from Uttarakhand, North India; were evaluated for antibacterial activity by Agar diffusion method against medically important bacteria viz. B. subtilis, K. pneumonia, E. coli, Enterobacter aerogenes, Pseudomonas aeruginosa, S. aure...

BACKGROUND Previous studies have described drug shortages; however, there has been no comprehensive evaluation focusing on US antibacterial shortages. METHODS Drug shortage data from the University of Utah Drug Information Service database were analyzed, with a focus on antibacterial agents from 2001 to 2013. We used descriptive statistics to describe trends in drug shortages, analyze drug cl...

The rationale behind this project work was to prepare neomycin sulphate loaded chitosan nanofibers via electrospinning methods so as to enhance wound healing property. Natural polymers are used as main compounds for design of therapeutic drug delivery systems for treatment of different ailments. Chitosan and Neomycin sulphate have proven wound healing properties individually. The combination of...

Objective: Intravascular catheter-associated infection has been increasing hospitalization in post-surgery patients mainly due to microbial colonization of the catheter surface and formation of a superficial biofilm layer. The present study is aimed in developing an effective antibacterial device which can prevent colonization of organisms by modification of catheter. Methods: In the present st...

background and objective: organisms producing ctx-m β-lactamases are emerging as a source of resistance to oxyiminocefalosporins such as ceftriaxone and ceftazidime. however, the laboratory detection of these strains is not well defined. in this study, phenotypic assay for screening of extended-spectrum β-lactamases producing strains and molecular assay for the identification of ctx-m β-lactama...

Antibiotic-loaded carriers were developed to fill cavities and locally deliver antibiotics following implantation. However, the most commonly used antibiotic carrier, polymethyl methacrylate (PMMA), has many disadvantages including that it does not promote bone regeneration or conduction. Vancomycin-loaded bone-like hydroxyapatite/poly amino acid (V-BHA/PAA) was successfully fabricated by a hom...