background recurrent urinary tract infection (uti) due to vesicoureteral reflux (vur) is common in iraq. endoscopic treatment of vur is used with advantages over antibiotic prophylaxis and ureteral reimplantation. objectives this study was performed to assess the efficacy of a new agent, dexell, for treating patients with vur and its ability to manage recurrent uti. materials and methods this r...

Background: Acute Respiratory Distress Syndrome (ARDS) is a life-threatening condition in patients with predisposing factors, among which sepsis is a common cause. There are no effective strategies to treat this syndrome except supportive therapies. Some preclinical studies suggest a potential therapeutic effect of mesenchymal stem cells (MSCs) on ARDS. However, data specifically evaluating the...

Tobramycin sulphate, a new aminoglycoside antibiotic, was injected intramuscularly (80 and 100 mg) and subconjunctivally (10 mg) into patients, and the concentrations of the drug in serum and aqueous humour were determined 1 hour after the injection by an agar wall diffusion plate method. The intramuscular administration of tobramycin produced insignificant and non-inhibitory concentrations in ...

PURPOSE Bacillus cereus causes the most virulent and refractory form of endophthalmitis. The authors analyzed the effectiveness of early treatment with vancomycin or gatifloxacin, with or without dexamethasone, for experimental B. cereus endophthalmitis. METHODS Rabbit eyes were injected intravitreally with 100 colony-forming units of B. cereus. At 2, 4, or 6 hours after infection, eyes were ...

Introduction Antibiotic resistance is an alarming development. One of the major causes of antibiotic resistance is the improper prescription of antibiotics. This study sought to assess prescription of antibiotics and corticosteroids following endodontic procedures by general dentists practicing in Qazvin City, Iran. Methods This descriptive cross-sectional study was conducted on all 108 ge...

Cephaloridine is a wide-spectrum antibiotic derived from cephalosporin and, despite similarities to penicillin, it can be used in the treament of infections in penicillin-sensitive patients. Riley, Boyle, and Leopold (I968) and Records (I969) have reported the intraocular penetration of cephaloridine into the aqueous after intramuscular and intravenous administration, and Moll, Crawford, and Mc...

Herein we examined the toxicity, penetration properties and ability of Fe2O3·nH2O magnetic nanoparticles extracted from silt of the Borovoye Lake (Krasnoyarsk, Russia) to bind an antibiotic. Experimental studies were carried out using magnetic nanoparticles alone and after antibiotic exposure in tissue samples from nasal mucosa, cartilage and bone (in vitro). Toxicity of particles was studied i...

Discussion. We previously reported bone and fat levels some I 2 times higher than those after systemic injection (Hoddinott et al 1990) and have now extended our sampling to provide a pharmacokinetic profile over the important 24 hours after operation (Fig. 1). The results indicate that the regional intravenous administration of a single 750 mg dose of cefuroxime gave satisfactory haematoma lev...

Since the U.S. Food and Drug Administration approved dextranomer/hyaluronic acid copolymer (Deflux) for the treatment of vesicoureteral reflux, endoscopic injection therapy using Deflux has become a popular alternative to open surgery and continuous antibiotic prophylaxis. Endoscopic correction with Deflux is minimally invasive, well tolerated, and provides cure rates approaching those of open ...