background acinetobacter has become an important cause of different infections such as wound infection, due to its great ability to survive and spread in hospital settings and to develop resistance against many antibiotics. objectives the aim of this study was to investigate the antibiotic resistance among isolates of acinetobacter from wound infections during a 7-year period, from 2005 to 2011...

 The present study was aimed to evaluate the antimicrobial resistance and the presence of antibiotic resistance genes in Vibrios spp. isolated from seafood. A total of 72 isolates of Vibrio in 6 species including V. parahaemolyticus, V. vulnificus, V. alginolyticus, V. harveyi, V. mimicus and V. cholerae were examined. The results revealed that all isolates were expressing multiple an...

............................................................................. V Summary in Swedish (Populärvetenskaplig sammanfattning)............ VII List of papers....................................................................... IX Abbreviations....................................................................... X History of antibiotics and the emergence of resistance..................

AIMS Transmissible plasmids captured from stream and soil bacteria conferring resistance to tetracycline in Pseudomonas were evaluated for linked resistance to antibiotics used in the treatment of human infections. METHODS AND RESULTS Cells released from stream sediments and soils were conjugated with a rifampicin-resistant, plasmid-free Pseudomonas putida recipient and selected on tetracycli...

BACKGROUND Most clinical isolates that exhibit a multi-drug resistant phenotype owe that resistance to over-expressed efflux pumps. Compounds that are efflux pump inhibitors (EPIs) reduce or reverse resistance to antibiotics to which the bacterial strain is initially resistant. We have evaluated non-antibiotics to reduce resistance of commonly encountered bacterial pathogens to antibiotics. M...

Active efflux confers intrinsic resistance to multiple antibiotics in Pseudomonas aeruginosa , including old disused molecules. Beside resistance, intracellular survival is another reason for failure eradicate bacteria with antibiotics.

background :    acinetobacter baumannii has become one of the most important causes of nosocomial infections in recent years. the organism seems to be resistant to most classes of antibiotics. carbapenems are considered the most effective drugs for treatment of these infections. however, increasing emergence of carbapenem resistant a. baumannii has become a major healthcare problem.   methods :...

Background & Aims: Acinetobacter spp. are non-fermenting gram-negative coccobacilli that have emerged in recent three decades as major causes of nosocomial infections. Acinetobacter baumannii is the most common pathogen causing a wide spectrum of infections. Acinetobacter infections are difficult to treat, due to both the intrinsic resistance of the pathogen and its ability to readily acquire n...