This review outlines the antimicrobial activity of secondary metabolites and lectins, compounds usually associated to defense mechanisms of plants. Secondary metabolites are separated into nitrogen compounds (alkaloids, non-protein amino acids, amines, alcamides, cyanogenic glycosides and glucosinolates) and nonnitrogen compounds (monoterpenes, diterpenes, triterpenes, tetraterpenes, sesquiterp...

Sakuranetin (1) is a rice flavanone-type phytoalexin. We have already reported that the metabolites from the detoxification of 1 by Pyriculariaoryzae are naringenin (2) and sternbin. In this study, we investigated whether the rice sheath blight fungus Rhizoctoniasolani, another major rice pathogen, can detoxify 1. The extract of R. solani suspension culture containing 1 was analyzed by LC-MS to...

The biological control is an alternative measure to agrochemicals to control fungal pathogens in agricultural production. We recently reported the utilization of an actinomycete to the biological control in horticultural plant. Tissue-cultured seedlings of horticultural rhododendron suffer from significant damage caused by Pestalotiopsis sydowiana, a major pathogen of rhododendron, during the a...

C. odorata L. is considered to be a plant weed that scattered in various climates. As weed, this contains variety of beneficial secondary metabolites. Several studies have shown the benefits leaf extract. This study reviews metabolite content and pharmacological activities A literature search was carried out obtain related use Secondary metabolites identified are alkaloids, flavonoids, tannins,...

Natural products produced by microorganisms are considered an important resource of bioactive secondary metabolites, such as anticancer, antifungal, antibiotic, and immunosuppressive molecules. Streptomyces the richest source natural via possessing a wide number metabolite biosynthetic gene clusters (SM-BGCs). Based on rapid development in sequencing technologies with advances genome mining, ex...

Plants are attacked by various phytopathogenic fungi. For many years, synthetic fungicides have been used to control plant diseases. Although synthetic fungicides are highly effective, their repeated use has led to problems such as environmental pollution, development of resistance, and residual toxicity. This has prompted intensive research on the development of biopesticides, including botani...

Dermatophytes, a group of keratinophilic fungi thriving on the keratin substrate are the etiological agents responsible for causing cutaneous infections. Dermatophytosis is currently treated with the commercially available topical and oral antifungal agents in spite of the existing side effects. Treatment of these cutaneous infections with secondary metabolites produced by marine microorganisms...

Bioassay-guided separation with an eye toward antifungal activity led to the isolation of the new alkaloid 5-(1̀,1̀-dimethylallyl)-8-hydroxyfuro[2-3-b] quinoline (1) and the known biscoumarin daphnoretin (2) as the active constituents of the chloroform extract obtained from the leaves of Ruta chalepensis. The structures of the metabolites were elucidated on the basis of their spectral characteris...

Chemical and biological investigations of the endophytic fungus of an unidentified Ascomycete, isolated from Meliotus dentatus led to the isolation of six known polyketide metabolites (1–6) and two steroids (7 and 8). Compounds 1–3, and 5 were tested for antibacterial, antialgal and antifungal activities. Compounds 2, 3, and 5 showed good activity against the alga Chlorella fusca, while compoun...