نتایج جستجو برای: antihypertension

تعداد نتایج: 147  

Journal: :Medical archives 2012
Zana Zegarac Zeljko Duic Sandra Stasenko Vanja Fenzl Jasenka Zmijanac-Partl Mladen Knotek

The kidney transplantation is considered to be the best therapy for terminal kidney disease, nowadays. Numerous studies have shown that pregnancy may be successful and may result in a delivery of a healthy baby after the kidney transplantation. Pregnant women who are the recipients of a kidney transplant have increased chances of developing hypertension, preeclampsia, as well as going into prem...

2015
Li Tan Weiwei Chen Ming-Yu Wei Jinhua Shen Meng-Fei Yu Guangzhong Yang Donglin Guo Gangjian Qin Guangju Ji Qing-Hua Liu

The traditional herb Plumula Nelumbinis is widely used in the world because it has many biological activities, such as anti-inflammation, antioxidant, antihypertension, and butyrylcholinesterase inhibition. However, the action of Plumula Nelumbinis on airway smooth muscle (ASM) relaxation has not been investigated. A chloroform extract of Plumula Nelumbinis (CEPN) was prepared, which completely...

Journal: :Medicinal Chemistry Research 2022

As prodrugs series of new sartan-derived molecules were designed, synthesized, and evaluated. Most the synthesized compounds could decrease blood pressure efficiently in spontaneously hypertensive rats. It be ratiocinated that original drugs released from exactly at connecting position catalyzed by hydrolyzation enzymes. The maximal response mean (MBP) lowered 70.2 ± 5.0 mmHg (compound I1) 61.2...

2016
Tien-Jyun Chang Wen-Chang Wang Chao A. Hsiung Chih-Tsueng He Ming-Wei Lin Wayne Huey-Herng Sheu Yi-Cheng Chang Tom Quertermous Ida Chen Jerome Rotter Lee-Ming Chuang

Essential hypertension is a complex disease involving multiple genetic and environmental factors. A human gene containing a sorbin homology domain and 3 SH3 domains in the C-terminal region, termed SORBS1, plays a significant role in insulin signaling. We previously found a significant association between the T228A polymorphism and insulin resistance, obesity, and type 2 diabetes. It has been h...

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