the current study evaluated the general toxicity, antioxidant, antimicrobial, and cytotoxic activity of extracts obtained from the rhizomes of eremostachys azerbaijanica (labiatae) as well as analyzed the potent extracts using gc-ms. extracts of e. azerbaijanica in n-hexane, dichloromethane (dcm) and methanol (meoh) were prepared using a soxhlet apparatus. the antioxidant activity of the extrac...

The increase in prevalence of antimicrobial-resistant bacteria (ARB) is currently a serious threat, thus there is a need for new antimicrobial compounds to combat infections caused by these ARB. An antimicrobial-producing bacterium, Burkholderia paludis was recently isolated and was able to produce a type of siderophore with antimicrobial properties, later identified as pyochelin. The chelating...

A population-based study combining (i) antimicrobial, (ii) genetic, and (iii) virulence analyses with molecular evolutionary analyses revealed segregative characteristics distinguishing human clinical and bovine Escherichia coli O157 strains from western Canada. Human (n = 50) and bovine (n = 50) strains of E. coli O157 were collected from Saskatchewan and Manitoba in 2006 and were analyzed by ...

The present work examines the potential of sesquiterpenoids to sensitize Escherichia coli and Staphylococcus aureus, and modulate their susceptibility to the standard antibiotics ciprofloxacin, erythromycin, gentamicin and vancomycin. It was tested samples of three sesquiterpenoids: guaiazulene, nerolidol (racemic mixture of the cis and trans isomers) and germacrene D enriched natural extract. ...

Objective: Our objective of this research work was to investigate antimicrobial activity of five species of traditionally used medicinal plants namely Adhatoda vasica, Artemisia annua, Cordia oblique, Croton bonplandianum and Euphorbia milli against different strains of bacteria and fungi which are known to cause various types of infectious diseases. Methods: Organic extracts of these plants le...

BACKGROUND Snakin-1 (StSN1) is a broad-spectrum antimicrobial cysteine-rich peptide isolated from Solanum tuberosum. Its biotechnological potential has been already recognized since it exhibits in vivo antifungal and antibacterial activity. Most attempts to produce StSN1, or homologous peptides, in a soluble native state using bacterial, yeast or synthetic expression systems have presented prod...

This study was designed to examine the in vitro antioxidant and antimicrobial activities and to characterize the polyphenolic composition of the ethanolic extracts of Hyssopus officinalis, Ocimum basilicum and Teucrium chamaedrys. Qualitative and quantitative analysis of the major phenolic compounds were conducted using high-performance liquid chromatography coupled to mass spectrometry (HPLC-M...

OBJECTIVES A wide selection of wound dressings is available on the market with varying claims of antimicrobial efficacy. A valid standard method for evaluation of their antimicrobial activity in vitro has not been established. In this study we suggest a standardized time-kill assay procedure for antimicrobial activity evaluation of wound dressings in order to make studies more comparable and re...