The present study evaluated the antimicrobial in vitro effects of the salivary proteins lactoferrin and lysozyme on microorganisms involved in the carious process, obtaining their minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Streptococcus mutans (ATCC 25175) and Lactobacillus casei (ATCC 7469) were submitted to broth macrodilution of lysozyme at 80 mg/mL ...

Nanotechnology is being envisioned as a hurriedly developing field, it has potential to revolutionize food systems and improve the conditions of the food quality. The present study reports the synthesis of ZnO nanoparticles using wet chemical method and used as antimicrobial agent against Food borne Pathogens. The antibacterial activity of ZnO nanoparticles was examined against E. coli, and Pse...

A total of 173 actinomycetes colonies were isolated from near shore marine environment and mangrove ecosystem at 8 different locations of Kerala, West Coast of India. Among them, 64 isolates were morphologically distinct on the basis of spore mass colour, reverse side colour, aerial and substrate mycelia formation and production of diffusible pigment. The majority (47%; n=30) of these isolates ...

Bacterial colonization and subsequent biofilm formation is still one of the major problems associated with medical devices. Antimicrobial peptides (AMP) immobilization onto biomaterials surface is a promising strategy to avoid bacterial colonization. However, a correct peptide orientation and exposure from the surface is essential to maintain AMP antimicrobial activity. This work aims to evalua...

background and aim: yogurt is one of the most consumed foods with different probiotic effects. the aim of this study was to evaluate antimicrobial effects of non-industrial yogurts on two common enteropathogens – salmonella and shigella. methods: in this experimental study, we evaluated the antimicrobial effects of 30 various non-industrial yogurt samples on 11 shigella sonnei, 7 shigella flexn...

The abundance of lysozyme on mucosal surfaces suggests that successful colonizers must be able to evade its antimicrobial effects. Lysozyme has a muramidase activity that hydrolyzes bacterial peptidoglycan and a non-muramidase activity attributable to its function as a cationic antimicrobial peptide. Two enzymes (PgdA, a N-acetylglucosamine deacetylase, and Adr, an O-acetyl transferase) that mo...

Pharmacodynamics describes the relationship between measures of drug levels in serum and tissue fluids and the antimicrobial and toxicologic effects of drugs (5, 10, 17, 49). While there have been numerous studies describing the pharmacokinetics of fluoroquinolones in serum and tissues, there has been much less emphasis on describing the time course of antimicrobial activity with these drugs. T...

Glass ionomer cements reportedly bond to tooth surfaces by physicochemical interaction and slowly release fluoride. 1 Two mechanisms are involved in fluoride release, a rapid surface elution and a slower bulk diffusion of fluoride ions. 2, 3 The greatest release of fluoride reportedly occurs in the first 24 hr, and then remains constant for several months before it tapers off after 2 years.4, 5...

A new heterogeneous photocatalyst was prepared by incorporation of methylene blue into ZSM-5 zeolite. This photocatalyst effectively absorbs light in visible range of the spectrum and when irradiated with visible light, it generates reactive oxygen species (ROS) in aqueous environment. Efficiency of the photocatalyst was tested on dechlorination of a model compound 4-chlorophenol and on growth ...

White spot lesions (WSLs) are irreversible damages in orthodontic treatment due to excessive etching or demineralization by microorganisms. In this study, we conducted a mechanical and cell viability test to examine the antibacterial properties of 0.2% and 1% bioactive glass (BAG) and silver-doped and zinc-doped BAGs in a primer and evaluated their clinical applicability to prevent WSLs. The mi...