the entomopathogenic-fungus-life cycle is associated with the synthesis and secretion of a number of toxic metabolites, including extracellular enzymes and the low-molecular weight compound (toxin). the potential for a successful pathogen relies on the ability to overcome the various host-defence systems. interaction between the fungus, tolypocla-dium (deuteromycetes), its secondary metabolite,...

Brassinosteroids (BRs) have been shown to induce hydrogen peroxide (H(2)O(2)) accumulation, and BR-induced H(2)O(2) up-regulates antioxidant defence systems in plants. However, the mechanisms by which BR-induced H(2)O(2) regulates antioxidant defence systems in plants remain to be determined. In the present study, the role of ZmMPK5, a mitogen-activated protein kinase, in BR-induced anitioxidan...

SUMMARY 12 Male-male aggression can have a large influence on access to mates, particularly in highly 13 territorial animals such as mice. It has been suggested that males with impaired antioxidant 14 defence and a consequential increased susceptibility to oxidative stress may have a reduced 15 ability to invest in aggressive behaviours, which could limit their mating opportunities and 16 repro...

Mussels are used as sentinel organisms and bioindicators to evaluate the toxic effects of chemical pollutants in marine organisms, especially heavy metals, representing an important tool for biomonitoring environmental pollution in coastal areas. Antioxidant defence enzymes play an important role in cellular antioxidant defence systems and protect from oxidative damage by reactive oxygen specie...

the close relationship between the immune system and the central nervous system (cns) has been well-studied. the cns regulates almost all the functions of the immune system; however, the effect and/or the control of the immune system on the cns has not been well-studied yet. recent reports suggest that the cns has its own defence mechanism(s). in this review, attempts have been made to discuss ...

Oxidative modification of plasma lipoproteins increases their atherogenicity. Nutritive antioxidants, including carotenoids, can prevent such lipoperoxidation and may protect against atherosclerosis. Plasma retinol, ascorbate, alpha-tocopherol and four carotenoids (lutein, lycopene, alpha-carotene and beta-carotene) were measured using HPLC in 45 patients with chronic renal failure (CRF) and in...

As noted by Warburg, many cancer cells depend on the consumption of glucose. We performed a genetic screen to identify factors responsible for glucose addiction and recovered the two subunits of the xCT antiporter (system xc-), which plays an antioxidant role by exporting glutamate for cystine. Disruption of the xCT antiporter greatly improves cell viability after glucose withdrawal, because co...