BACKGROUND The pathophysiology of migraine and other headaches is still unknown, and research is mostly done on neurotransmitter, biochemical and vascular mechanisms. The aim of this study was to examine the role of antioxidant enzymes in the pathophysiology of headache in the interictal period of the pain process. METHODS In this study, glutathione peroxidase, catalase and superoxide dismuta...

Microcystis aeruginosa is a major primary producer and a common toxic cyanobacterium, playing an important role in the aquatic environment (Chen et al., 2016). Microcystis aeruginosa is commonly observed in highly eutrophic lakes (Watanabe and Oishi, 1985). In recent years, surface cyanobacterial bloom occurred frequently in most large shallow lakes in China, such as Lake Taihu (Zhang et al., 2...

Exposure to estrogens and alcohol consumption - the two only well-established risk factors for breast cancer - are capable of causing oxidative stress, which has been linked to progression of breast cancer. Here, five functional polymorphisms in the antioxidant genes SOD1, CAT and GSR were investigated in 703 breast cancer case-control pairs in the Danish, prospective "Diet, Cancer and Health" ...

Antioxidant enzyme activities, superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) and total glutathione concentration were determined in guinea pig lung and liver over the final period of gestation (days 50-68) and at several ages post-partum. Pulmonary antioxidant capacity increased markedly over the final days of gestation, individual changes ranging from 29% (glutath...

Background: Oleuropein is a phenolic compound which is present in the olive leaf extract. The purpose of the present study was to investigate the neuroprotective effect of oleuropein as an antioxidant agent on the substantia nigra in aged rats. Methods: Twenty 18-month-old Wistar rats (450-550 g) were randomly divided into control and experimental groups. The experimental group received a daily...

Nine compounds have been isolated for the first time from Celtis africana, namely trans-N-coumaroyltyramine (1), trans-N-feruloyltyramine (2), trans-N-caffeoyltyramine (3), lauric acid (4), oleic acid (5), palmitic acid (6), lupeol (7), β-sitosterol (8) and oleanolic acid (9), respectively. Their structures have been elucidated by different spectroscopic techniques. The isolated compounds were ...

in this study, we investigated the cardioprotective effects of resveratrol. rats were intraperitoneally administered with resveratrol (25 mg/kg bw) or vehicle (ethanol 10%) for 7 days and their heart subjected to ischemia/reperfusion injury. isolated hearts were langendorff perfused, left ventricular functions as heart rate and developed pressure, as well as, heart antioxidant status were deter...

(GSH)-dependent antioxidant system is modulated in irradiated tissue and serum even after 24h of irradiation. However, dose-dependent effect on the system has not been clarified and there is no report on effect of irradiation to urinary GSH-dependent enzyme activities. Therefore, in present study, rats were exposed to a single X-irradiation at several doses; 1, 3, 5, and 7 Gy, and after 24h of ...