نتایج جستجو برای: antiplatelet therapy

تعداد نتایج: 658043  

2016
Ichiro Deguchi Takeshi Hayashi Hiroaki Neki Fumitaka Yamane Shoichiro Ishihara Norio Tanahashi Masaki Takao

We herein report three ischemic stroke patients who underwent emergency carotid artery stenting after receiving intravenous tissue plasminogen activator (t-PA) treatment. All patients received antiplatelet medications immediately before stent placement for loading as well as dual antiplatelet therapy after stenting. Under high-dose and dual antiplatelet therapy, none of the three patients showe...

Journal: :Circulation 2009
Kang-Yin Chen Seung-Woon Rha Yong-Jian Li Kanhaiya L Poddar Zhe Jin Yoshiyasu Minami Lin Wang Eung Ju Kim Chang Gyu Park Hong Seog Seo Dong Joo Oh Myung Ho Jeong Young Keun Ahn Taek Jong Hong Young Jo Kim Seung Ho Hur In Whan Seong Jei Keon Chae Myeong Chan Cho Jang Ho Bae Dong Hoon Choi Yang Soo Jang In Ho Chae Chong Jin Kim Jung Han Yoon Wook Sung Chung Ki Bae Seung Seung Jung Park

BACKGROUND Whether triple antiplatelet therapy is superior or similar to dual antiplatelet therapy in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention in the era of drug-eluting stents remains unclear. METHODS AND RESULTS A total of 4203 ST-segment elevation myocardial infarction patients who underwent primary percutaneous co...

Journal: :European urology 2008
Fleur I de Korte Jochem W van Werkum Peter L M Vijverberg Jurriën M Ten Berg

The current practice of withdrawing antiplatelet therapy before major surgery has been challenged by the introduction of coronary drug-eluting stents (DESs) since evidence is accumulating that a DES requires dual antiplatelet therapy for at least a year. The authors present a case demonstrating difficulty in decision-making when it comes to appropriate perioperative antiplatelet therapy. The pa...

Journal: :Annual review of medicine 2010
Carlo Patrono Bianca Rocca

Mechanisms of platelet inhibition are reviewed with emphasis on the pharmacokinetic and pharmacodynamic determinants of clinical efficacy and safety of antiplatelet drugs. Current developments in antiplatelet therapy are discussed in relation to both primary and secondary prevention of atherothrombotic complications. Interindividual variability in response to antiplatelet agents and new drug ta...

Journal: :Stroke 1994
T Komiya M Kudo T Urabe Y Mizuno

BACKGROUND AND PURPOSE Antiplatelet therapy is currently one of the methods for preventing transient ischemic attacks and cerebral thrombosis. Because antiplatelet agents are generally administered on a long-term basis, patient compliance is an important factor. The purpose of this study was to determine the compliance of patients during antiplatelet therapy by testing platelet aggregation. M...

2016
Dawid L Staudacher Paul M Biever Christoph Benk Ingo Ahrens Christoph Bode Tobias Wengenmayer

AIMS Bleeding is a frequent complication in patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO). An indication for dual antiplatelet therapy due to coronary stent implantation is present in a considerable number of these patients. The objective of this retrospective study was to evaluate if dual antiplatelet therapy (DAPT) significantly increases the high intrinsic bleeding r...

2018
Philip M Bath Lisa J Woodhouse Jason P Appleton Maia Beridze Hanne Christensen Robert A Dineen Lelia Duley Timothy J England Katie Flaherty Diane Havard Stan Heptinstall Marilyn James Kailash Krishnan Hugh S Markus Alan A Montgomery Stuart J Pocock Marc Randall Annemarei Ranta Thompson G Robinson Polly Scutt Graham S Venables Nikola Sprigg L M Christensen L Bentsen C Krarup Hansen T T Thomsen C Kruuse H H Jensen S S Hansen V Petrovic N Beridze N Kakabadze T Kherkheulidze D Kakabadze I Toidze N Lobjanidze N Akiashvili A Tevdoradze N Khizanishvili T Tsanava R Taylor I Iniesta J Kok J Duignan M Funnell P Cariga M Rodriguez I J Watson S Tennant M Macleod J Furnace H Gow J Irvine A Joyson S Nelson V Taylor M Smith R Bellfield B Hairsine R Davies A Dodd J Corrigan M Doherty A Ahmed C Denniss S Johnson-Holland K A Kay R Icart Palau G Auld P Daboo R Erande G Grimwood D Hove L Howaniec O Redjep R Rangasamay G Butt D Sandler J Reddan S Stafford J McIlmoyle S Maguire P Murphy J Chambers L Guthrie M Osborn A Steele M Burn A Benford A Misra D Hilton E O'Brien E Amis S Finlay J Mitchell O Geraghty K Harvey B Hazel S Mashate P Wilding M Sajid M Ball R Gascoyne R Sivakumar A Wright K Chatterjee S Booth H Eccleson C Kelly S Leason C Perkins D Bruce E Brown S Clayton M Garside G Rogers E Lawrence S Mahmood C Watchurst D Chadha L Glover L Holford K Smith D Walstow R Williams L O'Shea J Goodsell C Athulathmudali E Barbon R Namushi P Jacob L Johnson D Morse C McGhee O Speirs S Atkinson A Peacocke P Langhorne R Graham F Wright C McAlpine A Ravindrane M Bajoriene L Matter S Windebank E Giallombardo D Dellafera C Eglinton J Wilson D Broughton K Chapman L Dixon M Zaidi K Ayes J Kessell D Manawadu O Adegbaju J Aeron-Thomas K Anderson A Brigden E Cattermole J Good S Hassan E Khoromana L Lee-Carbon K Marks E Mckenzie N Sikondari M Cooper K Whysall I Wynter J Bamford A Hassan P Wanklyn M Kambafwile L Makawa D Waugh E Veraque MGG Soliman S Arif R Brown S Butler C Hewitt J Hindle A Pusalkar H Beadle K Chan M Siddiqui P Dangri S Buddha A Asokanathan A Mistri D Eveson K Musarrat L Manning S Anand P Christian S Khan C Patel M Sein J Banns E Gibson T Gordon Y Gruenbeck S Wong P Datta G Bateman L Jackson A Needle Y Duodu R Oliver C Padilla-Harris M Barber D Esson F Brodie C McInnes K Fotherby D Butler D Morgan K Preece A Willberry M Dent F Hammonds J Hunt C Vernon D O'Kane F Faola P Lai J O'Callaghan C Smith C Price R Lakey V Riddell A Smith G Storey S Munshi A Buck J Clarke N Gilzeane M Godfrey R Keshvara C Richardson J Roffe L Ryan F Shelton W Sunman A Tittle J Tomlinson K Whittamore G Wilkes P Owusu-Agyei N Temple D Mangion A Hardwick K Netherton A Mohd Nor B Hyams S Norman N Persad S Ragab C Dickson J Dube E Jinks K Knops B Wadams K Ali J Gaylard G Spurling L Sztriha T Ajao M Alao F K Chan P Webster P Howard T J Dobson L Hyatt D Sims J Cunningham B Esisi T Cassidy M Bokhari B McClelland B Mokoena G Gunathilagan S Jones M Reader G Thomas S Tilby P Findlay F Barrett F Leslie S Ross I Shread J Okwera J Howe F Harrington G Courtauld C Schofield R Donnelly M Maddula J Scott J Beavan K Muhidden I Memon M Clarke A Hedstrom L Mills A Hemsley A Bowring L Boxall H Kingwell S Keenan C Roughan A Manoj P Cox G Fletcher P Lopez H Emsley B Gregary A McLoughlin S Raj C Roffe N Abano A Barry A Butler R Carpio K Castro K Finney S Gomm J Hiden J Grocott S Lyjko H Maguire A Remegoso R Sanyal S Stevens I Natarajan J Chembala G Muddegowda A Warusevitane A Blight O Balazikova C Lawlor L Shaw D Button D Howcroft S Lucas B Madigan S McCann A Dixit A Barkat J Davis M Fawcett L Finlay H Guy C Hays V Hogg E Horsley C Hubbuck C Pringle C Stevenson K Storey T Thompson S Woodward A Banerjee C Allcock S Merotra C Douglass E Campbell R Jarapa M Johnes C Keaveney T Marsden Z Naing J Perez K Shaw T Black A Anthony C Clarke J Paterson K Deighton E Temlett C Blank C Doyle S Duty K Gill K Harkness C Kamara E Richards K Elfandi P Guyler P Harman C Khuoge S Kunhunny S Tysoe B Moynihan T Adedoyin N Chopra N Dayal R Ghatala N Jeyaraj I Jones F Kennedy L Kerin N Khanom S Lewis S Maheswaran L Montague M Niemierko J O'Reilly S Trippier F Watson P Wilkinson E Young K Dizayee H Cochrane J O'Connell L Mokoena E Osborne A Nair J Greig C Jenkins J Powell F Price M Chowdhury S Brixey L Hunt N Rands G Rose S Stoddart M Srinivasan N Motherwell R Shekhar T Fuller A Lankester P Lingwood C Rankin H Webb B Jupp J Bell G Hann B Longland C Ovington B Bhaskaran G Ayres C Bailey H Bearne J Buxton P Fitzell C Hilaire D Kelly S Szabo D Tomlin E Gamble B Charles R Kumar T Fluskey Z Mellor J Peters V Sutton A Kenton I Martin S Nyabadza S Ghosh M Henry B Kumar C Ambulo S Crawford T Nozedar M Platton V Cvoro M Couser K McCormick D Wilkinson K Javaid S Hurdowar T Attygalle S Sundayi O Orugun H Crowther R Jolly U Poultney A Azim M Krasinska-Chavez J White N Sengupta J Margalef M G Metiu S Meenakshisundaram S Dealing D Hargroves E Beranova L Cowie H Rudenko A Thomson A Verrion K Rashed S Board C Buckley D Hayward

BACKGROUND Intensive antiplatelet therapy with three agents might be more effective than guideline treatment for preventing recurrent events in patients with acute cerebral ischaemia. We aimed to compare the safety and efficacy of intensive antiplatelet therapy (combined aspirin, clopidogrel, and dipyridamole) with that of guideline-based antiplatelet therapy. METHODS We did an international,...

2013
Gérard Helft Claude Le Feuvre Jean Louis Georges Didier Carrie Florence Leclercq Hélène Eltchaninoff Alain Furber Fabrice Prunier Laurent Sebagh Simon Cattan Guillaume Cayla Eric Vicaut Jean-Philippe Metzger

BACKGROUND Dual antiplatelet therapy with aspirin and thienopyridine is required after placement of coronary drug-eluting stents (DES) to prevent thrombotic complications. Current clinical guidelines recommend at least 6 to 12 months of treatment after a DES implantation, but it may be beneficial to apply dual antiplatelet therapy for a longer duration. METHODS/DESIGN The optimal dual antipla...

2015
Andrej Markota Andreja Sinkovič Bogdan Čizmarević

Some patients who need dual antiplatelet therapy sometimes require tracheotomy. Aim of this study was to compare the rate of complications during and after surgical tracheotomy between patients requiring dual antiplatelet therapy and those without dual antiplatelet therapy. We retrospectively included 79 patients (62% men, mean age 64 ± 14 years) in the period 2007-2011. The following complicat...

2013
Rahul Saini

Haemostatic function of platelets is vital & their pathological role is potentially lethal. In pathological states there is over activation and aggregation of blood platelets resulting in atherothrombosis causes various states from angina to acute coronary syndromes, stroke and peripheral artery diseases. Platelets are anuclear subcellular fragments derived from megakaryocytes that circulate in...

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