The reactive species are part of normal human metabolism and are involved in many physiological mechanisms. However, when reactive species are overproduced and antioxidant defenses are insufficient to control oxidation, an unbalance can occur, leading to cellular oxidative damage. This injury has been associated with many diseases including inflammation, cancer, cardiovascular disease, diabetes...

Two of the major factors that should be considered in leaves extraction are the solvent type and extraction method. In the current study, the effects of two solvents (Ethanol and Methanol) and two extraction methods (soaking and soxhlet) on phenolics and flavonoid contents, antibacterial and antiradical properties of extracts were investigated in a factorial experiment based on completely rando...

The use of poly(N-vinyl-2-pyrrolidone) (PVP) hydrogel-supported luminol chemiluminescence (CL) for the automatic determination of hydrogen peroxide and the quantification of the antiradical capacity of Trolox is described. The hydrogel containing luminol and hemin is prepared directly on a 96-well microplate and can be stored for up to 3 months without significant decrease in CL quantum yields....

Antioxidant properties of substrates [flavanone (1), 6-hydroxy- (2), 7-hydroxy- (3), 5,7,4'-trihydroxy- (5), and 7-methoxyflavanone (4)] and products of their microbial transformations, comprising hydroxylation, O-methylation, stereospecific reduction, dehydrogenation, and C-ring cleavage of the benzo-gamma-pyrone system, were determined. Measurements of the antiradical activity (expressed as I...

In present study, the comparative in vitro free radical scavenging activities of methanol extracts from three indigenous medicinal plants viz. Amla, Bitter gourd and Neem were evaluated by 1, 1-diphenyl-2-picryl-hydrazil (DPPH) radical scavenging method. Ascorbic acid was used as the reference. All of the plant extracts exhibited promising antiradical effects in a concentration dependent manner...