SUMMARY In order to evaluate the long-ter m effects of antithyroids and ahlative therapy on patients with toxic diffuse goiter (TDG) in an iodine deficient region, 206 patients were studied in Tehran. Hyperthyroidism recurred in 50%, of 80 patients treated with Methimazole (MMI), from one week to 48 months after cessation of therapy. Another 40 patients remained in remission. Of 102 patients t...

BACKGROUND Creutzfeldt-Jakob disease and Hashimoto's encephalopathy often show similar clinical presentation. Among Creutzfeldt-Jakob disease mimics, Hashimoto's encephalopathy is particularly important as it is treatable with corticosteroids. Thus, in cases of middle-aged woman diagnosed with probable Creutzfeldt-Jakob disease and who exhibit high titers of antithyroid antibodies, corticostero...

21 Thyroid hormones are essential developmental factors, and Graves’ disease (GD) may 22 severely complicate a pregnancy. This review describes how pregnancy changes the risk of 23 developing GD, how early pregnancy by several mechanisms leads to considerable changes in the 24 results of the thyroid function tests used to diagnose hyperthyroidism, and how these changes may 25 complicate the dia...

Objective. Aim of the study was to determine the prevalence of autoimmune thyroid disease, persistence of antithyroid antibodies, effect of gluten-free diet, and long-term outcome of thyroid function in pediatric patients with celiac disease (CD). Methods. 67 patients with CD aged from 1 year to 16 years were screened for thyroid antithyroperoxidase, antithyroglobulin and anti-TSH receptor anti...

Confusion is a rare manifestation of thyrotoxicosis. The patient presented with an acute confusional state and had clinical and biochemical features of thyrotoxicosis. His illness was well controlled with antithyroid therapy. It is thus concluded that thyroid function should be evaluated in otherwise unexplained encephalopathy as response to treatment is dramatic and most rewarding.

SINCE thiouracil was introduced to clinical therapeutics in I943, antithyroid treatment for thyrotoxicosis has widely increased and proved more and more effective as the years have passed, partly as the result of experience but also through the use of more effective agents, such as carbimazole and methimazole. It is thus possible now to assess their relative value in comparison with surgical tr...