Among 1,000 selected compounds and antibiotics tested against all or portions of the tmnor spectrum (33 tumors), cytoxan was the most effective, having a marked inhibitory to complete inhibitory effect on ~6 out of 38 tumors. Cytoxan (50 mg /kg /day for mice; ~5 m g / k g / d a y for rats) had a destructive effect on well established 7-day-old Sarcoma T5~41, Carcinoma 10~5, Lewis bladder carcin...

MATERIALS AND METHODS Ascites tumors were implanted intraperitoneally (I.P.) with 0.1 ml. of a 1:5 dilution of packed cells except for the L1210 leukemia, for which 0.5 ml. of a 10 -4 dilution of ascitic fluid was used. The P1534 leukemia was implanted with 0.5 ml. of a 10 -4 spleen suspension. Implants of all other tumors, approximately 1 cu. mm., were implanted subcutaneously by trocar. Insul...

calotropis procera is a small, erect plant, which is used in several traditional medicines to treat many diseases. it is a native of most of the asian and african countries. all plant parts exude thick white milky juice (latex) on cut or break. this shrub has been known to possess analgesic, antitumor, antihelmintic, antioxidant, hepatoprotective, antidiarrhoeal, anticonvulsant, antimicrobial, ...

canarium l. is used in folk medicine as anti-inflammatory, antibacterial, antifungal, antitumor, heptoprotective, antioxidant, and anti diabetic properties. the present study investigeated the invivo anti-inflammatory activity of  essential oil obtained by hydrodistillation of resin of canarium strictum roxb. in the current study, anti-inflammatory activity of essential oil of canarium strictum...

recent studies have indicated the profound  anti-tumor activity of artemisinin's compounds,  among  which;  arteether  is an  oil-soluble derivative of  artemisinin with an endoperoxide bridge that can induce apoptosis in tumor cells but not in the normal cells. an experiment was carried out on tumor-bearing balb/c mice to estimate the effects of arteether  on  tumor  growth  and  antitumor  im...

Numerous monoclonal antibodies (mAb) targeting tumor antigens have recently been developed. Antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP) via effector cells such as tumor-infiltrating natural killer (NK) cells and macrophages are often involved in mediating the antitumor activity of mAb. CpG oligodeoxynucleotides (ODN) have a potent antitumo...