cough is a common reason for seeking medical advices for children. cough is a natural defense mechanism and can frequently occur in healthy children and can be increased by urban living and polluted cities. thus, previous history, cough exacerbations factors and quality of cough are very helpful in diagnosis of pathological cough. there are different definitions for chronic cough. in this artic...

Several therapeutic effects including hypnotic, antispasmodic, treatment of abdominal and chest pain and strengthening the heart have been described for the flowers of Rosa damascena. North American Indian tribes use a decoction of the roots obtained from the Rosa damascena plant as a cough remedy and to treat eye problem. Therefore, in the present study the antitussive effect of this plant in ...

BACKGROUND Ma-Xing-Gan-Shi-Tang (abbreviated as MXGST), an important Chinese herbal prescribed for cough, bronchial inflammation and fever from pneumonia, consists of four medicinal herbs, including Ephedrae herb, Semen Pruni Armeniacae, licorice and Gypsum. These components, especially Ephedrae and Semen Pruni Armeniacae, possess antitussive activities, but they have severe adverse effects. ...

Studies on the antitussive agents have been advanced with the development of bio assay for them. At the present time, a large number of non-narcotic synthetic antitussives are employed in the management of cough instead of narcotic antitussives. The evaluation method for antitussive activity was first reported by Ernst in 1938 (1), that is, coughing was induced by pinching the trachea of a cat ...

rosa damascena mill l., known as gole mohammadi in iran is one of the most important species of rosaceae family flowers. r. damascena is an ornamental plant and beside perfuming effect, several pharmacological properties including anti-hiv, antibacterial, antioxidant, antitussive, hypnotic, antidiabetic, and relaxant effect on tracheal chains have been reported for this plant. this article is a...

The cough is a protective reflex mechanism that removes foreign material and secretions from the bronchi and bronchioles of the airways; it is inappropriately stimulated in various situations like inflammation of the respiratory tract or neoplasia. In these cases, cough has a pathological character and it is necessary sometimes to use cough-suppressant drugs. The most frequently used antitussiv...

BACKGROUND Cough variant asthma (CVA) is a phenotype of asthma presenting solely with coughing, characterized by airway hyperresponsiveness, eosinophilic inflammation and a cough response to bronchodilators. Leukotriene receptor antagonists (LTRAs) are antiasthma medications with anti-inflammatory and bronchodilatory properties. Although LTRAs exert antitussive effects in CVA, the mechanisms in...