BACKGROUND AND PURPOSE One in 3 stroke survivors has aphasia (impaired language comprehension and expressive abilities). Conventionally, depression diagnosis uses language-based methods. We aimed to systematically review methods that have been used to diagnose depression and adaptations to these methods intended for people with aphasia. METHODS We systematically reviewed stroke studies (to Ja...

The present study was conducted on 56 patients (34 females, 22 males), presenting with aphasia due to ischemic insult in the domain of the MCA. Patients were divided into 2 groups to study the short and long-term changes of rCBF in various clinical types of aphasia. They were subjected to thorough neurological examination, assessment of aphasia using modified Chesher test and AAT, laboratory te...

Objectives: Wernicke’s aphasia is one of the most prominent focal brain deficits affecting the comprehension abilities of patients while preserving their production abilities. Although a lot of studies in different languages have been conducted to analyze the nature of this deficit, still some controversies exist in this regard. While some research studies attribute this defect to a performance...

BACKGROUND People with aphasia and their family members are at high risk of experiencing post stroke depression. The impact of early interventions on mood and quality of life for people with aphasia is unknown. METHODS/DESIGN This study will determine whether an early intervention for both the person with aphasia after stroke and their family members leads to better mood and quality of life o...

Topographical evaluation of aphasic brain lesions can enhance our knowledge of cognitive physiology and plasticity. This prospective study was conducted on 100 stroke-afflicted patients with aphasia admitted in Valie-Asr Hospital (Khorasan, Iran) in 2003. Topography of infarct lesions was detected by a neurologist based on the map of brain vascular territories in CT-scan. Aphasic lesions catego...

Despite being perhaps the most studied form of aphasia, the critical lesion location for Broca's aphasia has long been debated, and in chronic patients, cortical damage often extends far beyond Broca's area. In a group of 70 patients, we examined brain damage associated with Broca's aphasia using voxel-wise lesion-symptom mapping (VLSM). We found that damage to the posterior portion of Broca's ...

Background: A growing body of research in aphasia treatment has indicated that greater amount and intensity of treatment is associated with better outcomes in individuals with chronic aphasia. AphasiaScripts is a computerised conversational script training program that simultaneously collects accurate, reliable data about amount and intensity of treatment. Aims: The purpose of this study was fi...

This study investigated the vulnerability of lexical processing in individuals with aphasia. Though classical teaching of aphasia syndromes holds that people with Broca's aphasia have intact comprehension at the single-word level, the nature and extent of this purported sparing were explored under suboptimal processing conditions. A combination of acoustic distortions (low-pass filtering and ti...

Aphasia assessment is crucial in diagnosing aphasia, determining the extent of language impairment, and identifying factors that may support or restrict aphasia recovery to design an appropriate plan care for people with aphasia. Speech-language therapists (SLTs) play a major role conducting assessments. Little known about practices SLTs assessing low-resource regions. The present study aims id...

BACKGROUND AND PURPOSE Primary-progressive aphasia is a clinically and pathologically heterogeneous condition. Nonfluent, semantic, and logopenic are the currently recognized clinical variants. The recommendations for the classification of primary-progressive aphasia have advocated variant-specific patterns of atrophy. The aims of the present study were to evaluate the sensitivity and specifici...