نتایج جستجو برای: apoptosis ht 29 cells
تعداد نتایج: 1579517 فیلتر نتایج به سال:
Cationic antimicrobial peptides (AMPs) became a promising alternative to the conventional cancer drugs. We investigated the effects of 5 AMPs (melittin, galanin-mastoparan, cecropins A, B and P1) on the viability of HT-29 and AR-42J carcinoma cells. The viability of the cells was evaluated and used to calculate the AMPs therapeutic index. Also, cellular apoptosis and necrosis were analyzed. Mel...
Introduction: The imbalance of the microbial ecosystem causes biological changes associated with colorectal cancer and cell proliferation and their planned death, as well as the immune responses. The aim of this study was to determine the effect of probiotic bacteria on the expression of genes associated with growth, metastasis and apoptosis in cancer cells of the HT29 colon. Materials & Me...
Constitutive photomorphogenesis 9 signalosome (CSN) consists of a total of eight subunits (CSN1-CSN8) in mammalian cells. CSN6 may promote carcinogenesis by positively regulating v‑myc avian myelocytomatosis viral oncogene homolog (Myc) and MDM2 proto‑oncogene stability, and is regarded as a potential target for cancer therapy. Quercetin has a substantial anticancer effect on various human canc...
Title: Fucoidan present in brown algae induces apoptosis of HT-29 human colon cancer cells
The HT-29 colon cancer cell line was used in the current work to investigate anti-cancer efficacy of Gymnema sylvestre extracts. viability, apoptosis, flow cytometry, and mode action active fraction were also evaluated. fractions G. caused cycle arrest at S phase G2/M phase, programmed death. alcoholic showed effect cells. By applying methanolic cells, IC50 observed 140.39 μg/mL, whereas for ch...
In a systematic effort to identify a potent antiproliferative agent, four complexes of vanadium containing maltol and deferiprone ligands were synthesized and evaluated for their cytotoxic activity against five human and animal cancer cell lines, including human breast cancer cells (MCF-7), human cervix epithelial carcinoma (HeLa), human colon cancer cell line (HT-29), human leukemia cell line ...
AIM To investigate the effect of paeonol on controlling the proliferation of colorectal cancer cell line HT-29 and to discuss its possible mechanism. METHODS The inhibitory effect of paeonol on proliferation of HT-29 cells was detected by MTT assay. The results of apoptosis were measured by flow cytometry. Immunocytochemical staining was performed to detect the expression of cyclooxygenase-2 ...
20(S)-ginsenoside Rg3 [20(S)-Rg3)], one of the main constituents isolated from Panax ginseng, has been shown to have an anti-cancer effect and to induce apoptosis by interfering with several signaling pathways. However, the molecular mechanisms of AMP-activated protein kinase (AMPK) associated with apoptosis in HT-29 colon cancer cells remain unclear. In the present study, we investigated wheth...
The second generation peptide CIGB-552 has a pro-apoptotic effect on H460 non-small cell lung cancer cells and displays a potent cytotoxic effect in HT-29 colon adenocarcinoma cells though its action mechanism is ill defined. Here, we present the first proteomic study of peptide effect in HT-29 cells using subcellular fractionation, protein and peptide fractionation by DF-PAGE and LC-MS/MS pept...
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