In this study accumulative roll bonding (ARB) process up to 8 Cycles (equivalent strain of 6.4) at ambient temperature was used in order to improve the mechanical properties of Commercial purity titanium (CP-Ti).Several experiment has been done and Mechanical properties of specimen has been discussed. For investigating optical microscope punching and hardness test were utilized. This is the fir...

In this study accumulative roll bonding (ARB) process up to 8 Cycles (equivalent strain of 6.4) at ambient temperature was used in order to improve the mechanical properties of Commercial purity titanium (CP-Ti).Several experiment has been done and Mechanical properties of specimen has been discussed. For investigating optical microscope punching and hardness test were utilized. This is the fir...

We showed previously that angiotensin II activated the proliferation of prostate cancer cells and that angiotensin II receptor blockers (ARB) could inhibit it. Here, we investigated whether angiotensin II exerts mitogenic effects on the cross-talk between stromal and cancer cells and whether an ARB can inhibit tumor growth through actions on stromal cells. Cell proliferation and interleukin-6 s...

An ultra low carbon interstitial free (IF) steel was severely deformed by the six-layer stack accumulative roll-bonding (ARB) process for improvement of the mechanical properties. As-received material with 1mm in thickness showed a recrystallization structure with average grain diameter of 27mm. The ARB was conducted at ambient temperature after deforming the as-received material to 0.5mm thick...

Angiotensin type 1 (AT1) receptor blocker (ARB) ameliorates progression of chronic kidney disease. Whether this protection is due solely to blockade of AT1, or whether diversion of angiotensin II from the AT1 to the available AT2 receptor, thus potentially enhancing AT2 receptor effects, is not known. We therefore investigated the role of AT2 receptor in ARB-induced treatment effects in chronic...

The efficacy and tolerability of eplerenone, a selective aldosterone blocker, was assessed when added to existing antihypertensive therapy with an ACE inhibitor or an angiotensin II receptor blocker (ARB). Hypertensive patients (n=341) whose blood pressure (BP) was not controlled despite ACE inhibitor or ARB were randomized (double-blind) to receive 50 mg eplerenone (increasing to 100 mg if req...

BACKGROUND Human exposure to antibiotic resistant bacteria (ARB) is a public health concern which could occur in a number of ways. Wastewaters seem to play an important role in the dissemination of bacteria and antibiotic resistant genes (ARGs) in our environment. The aim of this study was to evaluate the occurrence of three groups of ARB and their resistance genes in hospital and municipal was...

BACKGROUND Angiotensin II receptor blocker (ARB) as a first-line drug for hypertension in diabetes often fails to control blood pressure adequately. The objective of the study was to evaluate the effect of amlodipine combined therapy on home blood pressure (HBP) useful for management of hypertension. METHODS AND RESULTS A total of 263 type 2 diabetes with hypertension refractory to standard d...

BACKGROUND To assess the efficacy of aliskiren in patients failing to reach blood pressure (BP) goals with angiotensin converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB). METHODS A total of 107 patients who failed to reach BP goals on ACEI or ARB were switched to aliskiren. Changes in BP were determined during maximal ACEI, ARB, or aliskiren therapy. RESULTS Mean reduc...