Background SIRT1 plays a protective role against diabetic retinopathy as it regulates inflammation, apoptosis and autophagy of cells. Objectives This study was designed to investigate the effects arbutin identify potential mechanism action. Adult human retinal pigment epithelial (ARPE-19) cells were exposed high glucose (HG) or treated with different concentrations arbutin. Material methods The...

The cel (cellobiose utilization) operon of Escherichia coli K12 is not expressed in the wild-type organism. However, mutants that can express the operon and thereby utilize the P-glucoside sugars cellobiose, arbutin and salicin are easily isolated. Two kinds of mutations are capable of activating the operon. The first involves mutations that allow the repressor to recognize the substrates cello...

Optimization of cleaning and analytical method for determination arbutin, hydroquinone kojic acid in cosmetic products

objective:diabetes mellitus is a common metabolic disorder that is one of the important factors in the etiology of injuries oxidant know the purpose the aim of the present study, was the effect of swimming training with arbutin on total oxidant status (tos) and total antioxidant status(tas) the kidney tissue of alloxan-induced diabetic rats.methods: for this purpose, 42 male wistar rats with an...

INTRODUCTION Enzymatic polymerization has been extensively developed over the past two decades.1–7 In particular, horseradish peroxidase (HRP) has been used for enzymatic oxidative polymerization of phenolic compounds. Dordick and co-workers8,9 reported HRP-catalyzed polymerization of arbutin, a glucose-bearing phenol derivative. Water-soluble polyarbutins with molecular weight (Mn) in the rang...

Arbutin is the main active ingredient in many herbal medicinal products that have diuretic, antimicrobial, bactericidal, and antioxidant effects. Many of these are mixtures different substances. Therefore, approaches to quality control HMPs can vary significantly. The aim study was compare arbutin assay procedures used arbutin-containing products. Materials methods. Samples following were study...

Introduction: Interactions of free radicals from ionizing radiation with DNA can induce DNA damage and lead to mutagenesis and carsinogenesis. With respect to radiation damage to human, it is important to protect humans from side effects induced by ionizing radiation. In the present study,the effects of arbutin were investigated by using the micronucleus test for anti- clastog...

With regard to the importance of antioxidants in foods, cosmetics and pharmaceutics, there are several studies on natural resources for finding rich sources of antioxidants and their role in protecting the body against oxidative stress injuries. The purpose of this study was to investigate the antioxidant stability of arbutin and the Pyrus boissieriana buhse Leaf extract and their effects on li...