OBJECTIVE Platelet-rich plasma (PRP) has the capacity to improve the bone-healing process. The aim of this pilot study was to investigate the occurrence of bone healing and the time taken to achieve this in patients submitted to medial opening wedge high tibial osteotomy (MOWHTO), comparing platelet-rich plasma with bone marrow aspirate to autologous iliac graft. DESIGN Twenty-five patients w...

Bone marrow biopsies (244) performed with a Jamshidi needle were evaluated in 53 children with leukemia or aplastic anemia. Adequate specimens were obtained in 85%. Results of cellularity estimated by biopsy were compared to the cellularity of the aspirate versus volumetric determination of the myeloid-erythroid layer (buffy coat). A wide discrepancy was noted between marrow cellularity confirm...

Figure 1. Atypical and multinucleated plasma cell infiltration in the bone marrow aspirate (Wright's stain, 100x). A 66-year-old male patient was admitted to the hospital with backache, fatigue, and paraesthesia and spasm in both legs. He had lower extremity numbness and bladder and bowel incontinence. Physical examination revealed the absence of bilateral lower extremity reflexes and lower ext...

The authors describe an unusual presentation of lupus vulgaris in a 5-year-old boy. The lesions had a linear arrangement with proximal spread mimicking sporotrichosis. Histopathology of the lesions revealed tuberculoid granulomas. Tubercular etiology was confirmed by the demonstration of acid fast bacilli in the smears from the regional lymph node aspirate stained with Ziehl Neelsen stain, and ...

Fig. 1. (A–C) Features of the bone marrow (BM) aspirate and biopsy showing hemophagocytic lymphohistiocytosis (HLH) and cytomegalovirus (CMV) staining. (A, B) BM aspirate showing histiocytic hyperplasia and prominent hemophagocytosis by activated histiocytes. Arrowheads indicate features suggestive of ongoing endocytosis (Wright-Giemsa stain, ×1,000). (C) BM core biopsy result showing positive ...

One hundred and sixty six bone marrow aspirates from children with abdominal neuroblastoma were independently examined for the presence of neuroblastoma cells by conventional haematological staining techniques and by indirect immunofluorescence using one or more of five monoclonal antibodies. Results using the two methods were evaluated by comparison with the results of bone marrow, bone and ly...

Fig. 1. (A) Peripheral blood smear showing mature lymphocytes with dense chromatin, no nucleoli, and scanty agranular cytoplasm (Wright-Giemsa stain, ×1,000). (B) Bone marrow lymphocytosis on aspirate (Wright-Giemsa stain, ×1,000). toplasmosis diagnosed on bone marrow aspirate cytology: report of four cases. East Afr Med J 2009;86(Suppl 12):S102-5. 3. Caldwell CW, Taylor H. Visualization of his...

Nondiagnostic thyroid fine-needle aspirations are associated with a risk of malignancy that can be reduced with repeated aspiration. However, the significance of repeated nondiagnostic aspirates is less well studied. This study assessed the risk of malignancy for repeated nondiagnostic aspirates from a large series of cases using the results of histologic follow-up. From a series of 7,089 aspir...

OBJECTIVE To show the value of serial endotracheal aspirate culture in predicting organisms causing sepsis in ventilated neonates. METHODS We studied 100 newborns in Zeynep Kamil Maternity and Children's Training and Research Hospital Neonatal Intensive Care Unit. Endotracheal aspirate and blood cultures were taken first on the third day and then once a week till extubation. RESULTS Blood a...

BACKGROUND Isolation of tracheal aspirate mesenchymal stromal cells (MSCs) from premature infants has been associated with increased risk of bronchopulmonary dysplasia (BPD). MSCs show high levels of mRNAs encoding matricellular proteins, non-structural extracellular proteins that regulate cell-matrix interactions and participate in tissue remodeling. We hypothesized that lung matricellular pro...