نتایج جستجو برای: atc codes
تعداد نتایج: 79745 فیلتر نتایج به سال:
BACKGROUND As an extracellularly released mediator, high-mobility group box 1 (HMGB1) initiates sterile inflammation following severe trauma. Serum HMGB1 levels correlate well with acute traumatic coagulopathy (ATC) in trauma patients, which is independently associated with higher mortality. We investigated the involvement of HMGB1 in ATC through blocking extracellular HMGB1. MATERIAL AND METHO...
Anaplastic thyroid carcinoma (ATC) remains one of the most lethal human cancers. We hypothesized that sorafenib, a multikinase inhibitor of the BRaf, vascular endothelial growth factor receptor-2, and platelet-derived growth factor receptor-beta kinase, would decrease tumor growth and angiogenesis in an orthotopic model of ATC. The in vitro antiproliferative and proapoptotic effects of sorafeni...
NGS based identification of mutational hotspots for targeted therapy in anaplastic thyroid carcinoma
CONTEXT Anaplastic thyroid carcinoma (ATC) represents one of the most aggressive carcinomas with no consistent survival benefit when treated with conventional radiochemotherapy. Approaches targeting "oncogene addiction" of ATC are increasingly explored and first promising results have been reported in single case studies. OBJECTIVE To determine the prevalence of mutations in known thyroid onc...
Air traffic control (ATC) is based on voice communication between pilots and controllers and uses a highly task and domain specific language. Due to this very reason, spoken language technologies for ATC require domain-specific corpora, of which only few exist to this day. The ATCOSIM Air Traffic Control Simulation Speech corpus is a speech database of non-prompted and clean ATC operator speech...
Anaplastic thyroid carcinoma (ATC) is a frequently lethal malignancy that is often unresponsive to available therapeutic strategies. The tumorigenesis of ATC and its relationship to the widely prevalent well-differentiated thyroid carcinomas are unclear. We have analyzed 22 cases of ATC as well as 4 established ATC cell lines using whole-exome sequencing. A total of 2674 somatic mutations (121/...
Anaplastic thyroid carcinoma (ATC) although rare is the most lethal form of thyroid cancer. The mortality rate for ATC is very high, with a median survival time of only 5 months; the survival rate at 1 year after diagnosis is <20%. Management of ATC is extremely difficult and rife with uncertainties. Herein, we describe a 75-year-old woman who presented with ATC and was successfully treated usi...
In this paper, an optimal power flow based approach has been applied for multi-transactions deregulated environment for ATC determination with SVC and STATCOM. The main contribution of the paper is (i) OPF based approach for evaluation of ATC with multi-transactions, (ii) ATC enhancement with FACTS devices viz. SVC and STATCOM for intact and line contingency cases, (iii) Impact of ZIP load on A...
An interdisciplinary pharmacoeconomic study of pharmacotherapy for the relief alcoholic dependence on basis experimental clinical and pharmacological, organizational, legal marketing studies. The scheme basic drunken forms alcohol developed by authors was used. Thirteen international nonproprietary names drugs from Ukrainian (92.3%) foreign (7.7%) manufacturers were selected. It established tha...
Abstract Background Rare diseases are life-threatening, serious, and chronic conditions that require complex care have a low prevalence. An estimated one in 15 people worldwide affected by rare diseases. This study aims to analyze the accessibility, reimbursement status, licensed Anatomical Therapeutic Chemical (ATC) codes of drugs European Medicines Agency (EMA) Turkey considers be “orphan” ph...
Recent increase in air traffic demands makes the role of Air Traffic Control (ATC), which supports safety and efficiency of aviation, more important than ever. As aviation technologies have progressed, automation and computer supports are being introduced in cockpits, but ATC still heavily relies on human expertise of Air Traffic Control Officers (ATCOs). It is therefore necessary to understand...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید