An atlas-based segmentation approach is presented that combines low-level operations, an affine probabilistic atlas, and a multiatlas-based segmentation. The proposed combination provides highly accurate segmentation due to registrations and atlas selections based on the regions of interest (ROIs) and coarse segmentations. Our approach shares the following common elements between the probabilis...

The purpose of this study is to evaluate the use of the Dosimetry Check system for patient-specific IMRT QA. Typical QA methods measure the dose in an array dosimeter surrounded by homogenous medium for which the treatment plan has been recomputed. With the Dosimetry Check system, fluence measurements acquired on a portal dosimeter is applied to the patient's CT scans. Instead of making dose co...

The Open Anatomy Browser (OABrowser) is an open source, web-based, zero-installation anatomy atlas viewer based on current web browser technologies and evolving anatomy atlas interoperability standards. OABrowser displays three-dimensional anatomical models, image cross-sections of labeled structures and source radiological imaging, and a text-based hierarchy of structures. The viewer includes ...

Multi-atlas based methods have been recently used for classification of Alzheimer's disease (AD) and its prodromal stage, that is, mild cognitive impairment (MCI). Compared with traditional single-atlas based methods, multiatlas based methods adopt multiple predefined atlases and thus are less biased by a certain atlas. However, most existing multiatlas based methods simply average or concatena...

In internal radionuclide therapy, a growing interest in voxel-level estimates of tissue-absorbed dose has been driven by the desire to report radiobiologic quantities that account for the biologic consequences of both spatial and temporal nonuniformities in these dose estimates. This report presents an overview of 3-dimensional SPECT methods and requirements for internal dosimetry at both regio...

Introduction: The conventional methods of dosimetry are not capable of dosimetry in such a small volume of less than one cubic millimeter. Although the polymer gel dosimetry method based on magnetic resonance imaging (MRI) could achieve three dimensional dosimetry with high resolution, a spatial resolution evaluation based on gel dose modulation transfer function has not been investigated yet. ...