Introduction: The infection by Trypanosoma cruzi is a public health problem and there no effective treatment currently. Immunomodulatory effects of Atropa belladonna may offer benefits1 Objective: To evaluate the effect A. in murine T. cruzi. Methodology: experiment was blind, controlled randomized draw. Eighty five Swiss male mice, at 8 weeks age, were infected with 1400 blood trypomastigotes ...

Putrescine N-methyltransferase (PMT) is the first alkaloid-specific enzyme for nicotine and tropane alkaloid formation. The pmt gene from Nicotiana tabacum was fused to the CaMV 35S promoter and integrated into the Atropa belladonna genome. Transgenic plants and derived root cultures were analysed for gene expression and for levels of alkaloids and their precursors. Scopolamine, hyoscyamine, tr...

This investigation was carried out to improve the germination percentage and alkaloid 1 production in M seeds (irradiated seeds with 50, 80, 110 and 150 Gy) of Atropa belladonna L. by using and different concentrations of gibberellic acid (20,40,60,80,100 and 120 ppm). There was an increase in seed germination percentage by increasing gamma-ray doses until 150 Gy which gave 3 decrease in seed g...

Polyploidy is a prominent process in plant evolution and adaptation, but molecular phylogenetic studies of polyploids based on DNA sequences have often been confounded by their complex gene and genome histories. We report here a retroposon insertion in the nuclear gene granule-bound starch synthase I (GBSSI or "waxy") that clearly reveals the ancient hybrid history of the medically important po...

the solanaceae plants produce a variety of interesting biologically active products including the steroid alkaloids solanidine, nicotine and tropane alkaloids. putrescine n-methyltransferase (pmt) is an enzyme that catalyses s-adenosylmethionine-dependent methylation of putrescine in one of the primary steps of nicotine and tropane alkaloids biosynthesis pathway. two tobacco members of the ap2/...