The aim of this study was to determine the plaque-removing ability of curved bristle toothbrush compared to conventional, straight bristle, toothbrush The study group consisted of 100 children 12 to 16 years of age. A four week postprophylaxis, parallel, longitudinal, double-blind clinical study was conducted; all volunteers were instructed in specific oral hygiene techniques. Plaque was assess...

We have conducted genetic analyses of 12 long-term selection lines of Drosophila melanogaster derived from a highly inbred base population, containing new mutations affecting abdominal and sternopleural bristle number. Biometric analysis of the number of effective factors differentiating the selected lines from the base inbred indicated that with the exception of the three lines selected for in...

Advances in medicine, agriculture, and an understanding of evolution depend on resolving the genetic architecture of quantitative traits, which is challenging since variation for complex traits is caused by multiple interacting quantitative trait loci (QTL) with small and conditional effects. Here, we show that the key developmental gene, hairy (h), is a QTL for Drosophila sternopleural bristle...

BACKGROUND Genes of the achaete-scute complex encode transcription factors whose activity regulates the development of neural cells. The spatially restricted expression of achaete-scute on the mesonotum of higher flies governs the development and positioning of the large sensory bristles. On the scutum the bristles are arranged into conserved patterns, based on an ancestral arrangement of four ...

Many developmental processes rely on cortical actin dynamics; however, the mechanisms of its fine control at the cell cortex are still largely unknown. Our analyses demonstrate that the lipid- and F-actin-binding protein Abp1 is crucial for actin-driven bristle development in Drosophila melanogaster. Combined genetic, cell biological and biochemical analyses reveal that Abp1 triggers cortical A...

A closed-form solution for deflections and stresses in an annular thin plate of radially functionally graded material under transverse uniform pressure loading is presented. The small displacement theory of elasticity is assumed in the present work. Young’s modulus of the material is taken in the form of a simple power law to vary in the radial direction with an arbitrary exponent showing heter...

1. Single-unit responses to whisker deflections were studied in the rat somatosensory cortex (SI) under urethan anesthesia. 2. Experiments were concerned primarily with cortical layer V neurons, by selecting those units that 1) displayed initially positive biphasic spikes with an amplitude of at least 2 mV, 2) were located between 1,000 and 1,500 pm below the cortical surface of whisker C3 repr...

Developmental stability is widely regarded as a condition-dependent trait, but its relation to genotype and environment, and extent of developmental integration, remain contentious. In Telostylinus angusticollis, the dorsocentral bristles exhibit striking variation in developmental stability, manifested as fluctuating asymmetry (FA) in bristle position ('positional FA') and failure to develop s...

The Enhancer of split complex [E(spl)-C] in Drosophila encompasses a variety of functional elements controlling bristle patterning and on the basis of prior work is a strong candidate for harboring alleles having subtle effects on bristle number variation. Here we extend earlier studies identifying associations between complex phenotypes and polymorphisms segregating among inbred laboratory lin...