Introduction: For cell-based therapies of lung injury, several cell sources have been extensively studied. However, the potential human fetal respiratory cells has not systematically explored for this purpose. Here, we hypothesize that these could be one top and hence, updated definition their phenotype. Methods: Human lower tissues from pseudoglandular canalicular stages isolated epithelial we...

BACKGROUND Fluorescence membrane markers are efficient tools for visualizing the dynamics of membrane recycling processes in living cells. The outer hair cell (OHC) - a bipolar epithelial cell in the cochlea - possesses endocytic activity at both its apical and basal poles. The best visual overview of transcytosis in the OHC is achieved when the cell is isolated, so that both the apical and the...

Background and Objective: Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are two common tumors of the skin. In some cases, distinction between BCC and SCC can be difficult. This study aimed to clarify this uncertainty through immunohistochemical analysis. In this respect, epithelial membran...

background: several echocardiographic markers have been introduced to assess the left ventricular (lv) mechanical dyssynchrony. we studied dyssynchrony markers and the latest lv activation site in heart failure patients with and without left bundle branch block (lbbb). methods: conventional echocardiography and tissue velocity imaging were performed for 78 patients (lv ejection fraction ≤ 35%),...

basal cell carcinoma (bcc) is the most common cancer of the skin. definite diagnosis usually requires histological examination but recently it has been suggested that cytological examination of skin smear can be used as an alternative. to evaluate sensitivity and specificity of cytological examination, a total of 125 skin lesions, clinically suspected to be bcc were studied. cytological samples...

BACKGROUND - Basal cell carcinoma is the most common form of human cancer. Studies employing molecular and genetic biology techniques, associated with histomorphology, lead to the identification of risk factors in the development of more recurring and aggressive lesions. OBJECTIVE - To correlate markers expression of apoptosis (p53 and bcl-2) and cell proliferation (Ki-67 and PCNA) with histolo...

Precise regulation of stem cell self-renewal/differentiation is essential for embryogenesis and tumor suppression. Drosophila neural progenitors (neuroblasts) align their spindle along an apical/basal polarity axis to generate a self-renewed apical neuroblast and a differentiating basal cell. Here, we genetically disrupt spindle orientation without altering cell polarity to test the role of spi...