Understanding the intra-tumoral distribution of chemotherapeutic drugs is extremely important in predicting therapeutic outcome. Tissue mimicking gel phantoms are useful for studying drug vitro but quantifying laborious due to need section over relevant time course and individually quantify elution. In this study we compare a bespoke version traditional phantom sectioning approach, with novel c...

In this paper, we present a novel approach to enhance the sensitivity of microfluidic biosensor platforms with self-assembled magnetic bead chains. An adjustable, more than 5-fold sensitivity enhancement is achieved by introducing a magnetic field gradient along a microfluidic channel by means of a soft-magnetic lattice with a 350 μm spacing. The alternating magnetic field induces the self-asse...

This paper explains an integrated method of using genetic algorithm on the experimental data for optimizing the process parameters for height to width ratio and use of artificial neural network techniques for predicting the effects on the four weld bead geometric descriptors (front height, front width, back height and back width) by the five controlling weld process variables (welding speed, wi...

The notion of a bead metric space is defined as a nice generalization of the uniformly convex normed space such as $CAT(0)$ space, where the curvature is bounded from above by zero. In fact, the bead spaces themselves can be considered in particular as natural extensions of convex sets in uniformly convex spaces and normed bead spaces are identical with uniformly convex spaces. In this paper, w...

The magnetic force experienced by a soft magnetic bead is proportional to the strength of the field at the location of the bead. It is also proportional to the gradient of the field at that location. In general the analytical calculation of this force is intractable. However if the generation of the field can be abstractly modeled by a small number of magnetic monopoles, an analytical solution ...

adsorption and water treatment of ca (ii) and mg (ii) hardness were investigated via adsorption of metal ions onto commercial polyacrylic acid hydrogel beads as a novel sorbent for metal ions (ca2+, mg2+) removal and water treatment. batch equilibrium technique was carried out under the influence of solution ph, contact time, sorbent dosage, initial metal concentration and competitive study. th...

We describe a microfluidic system that uses a magnetic field to sort paramagnetic beads by deflecting them in the direction normal to the flow. In the experiments we systematically study the dependence of the beads' deflection on bead size and susceptibility, magnet strength, fluid speed and viscosity, and device geometry. We also develop a design parameter that can aid in the design of microfl...

Electron beam welding has proved phenomenal in welding of components used in space because it uses a vacuum environment which eliminates substances like oxygen, nitrogen, and hydrogen. The main advantage of EBW is its ability to weld dissimilar materials and incorporate desirable properties in the assembly. It has high depth to width ratio and focuses exactly on the portion to be welded, thereb...