High quality single Josephson junctions and junction arrays with 10 junctions in series have been fabricated using masked proton beam irradiation damage technology. Monte Carlo simulation of the irradiation damage profile underneath the metal mask has been carried out systematically to guide the metal mask structure design. A high resolution and high aspect ratio metal mask opening was fabricat...

PURPOSE In recent years experimental data have indicated that low-energy proton beam radiation might induce a difference in cellular migration in comparison to photons. We therefore set out to compare the effect of proton beam irradiation and X-rays on the survival and long-term migratory properties of two cell lines: uveal melanoma Mel270 and skin melanoma BLM. MATERIALS AND METHODS Cells tr...

OBJECTIVE Development of a technique for treating whole-body skin using linear accelerator with electron beam energy of 6-MeV at a short treatment distance. MATERIAL AND METHODS The 6 MeV high dose rate total skin electron irradiation mode on a linear accelerator was used. Beam profiles and percentage depth doses in the patient plane were measured for different beam angulations. RESULTS At ...

This paper presents our studies on surface modification of silicone elastomer by collagen grafting/coating and electron beam irradiation. Two types of collagen hydrolysates with different molecular weights were obtained and characterized, which were used in experiments. Both silicone elastomer crosslinking and collagen grafting on the surface of silicone elastomer were achieved by electron beam...

Particle radiotherapy such as proton and carbon ion has been producing promising clinical results worldwide. The purpose of this study was to compare metastatic capabilities of malignant tumor cells after irradiation with photon, proton, and carbon ion beams to clarify their ion beam-specific biological effects. We examined the biological properties of highly aggressive HT1080 human fibrosarcom...

AIM To describe the inflammatory reaction that can occur following proton beam irradiation of uveal melanomas based on a large series of patients and to try to determine the risk factors for this reaction. METHODS Data from a cohort of patients with uveal melanoma treated by proton beam irradiation between 1991 and 1994 were analysed. The presence of inflammation was recorded and evaluated. K...

LLE Review, Volume 79 149 In the direct-drive approach to inertial confinement fusion (ICF), capsules are irradiated directly by a large number of symmetrically arranged laser beams.1,2 Nonuniformities in the laser irradiation may seed the Rayleigh–Taylor hydrodynamic instability, which degrades target performance;3 therefore, a combination of beam-smoothing techniques is employed to achieve th...

Introduction: In the treatment of breast cancer, breast conserving surgery (BCS) and whole breast irradiation is a usual technique. The influence of lumpectomy boost following breast radiotherapy is apparent, but there are different delivery methods. This work intended to compare the dosimetric parameters of electron beams and photon beams for boosting irradiation in breast can...

Low-dose, low-penetration electron beam (E-beam) irradiation was evaluated for potential use as an antimicrobial intervention on beef carcasses during processing. The objectives of this study were (i) to assess the efficacy of E-beam irradiation to reduce concentrations of Escherichia coli O157:H7 on a large beef surface and (ii) to evaluate the effect of the treatment on the sensory properties...

For radiotherapy with external beams, quality assurance (QA) of beam delivery is mandatory. Dynamical irradiation which changes parameters of beam delivery devices during the irradiation has to be assessed with a great caution. At GSI a dynamic beam delivery system, so called beam tracking system [1] was developed and integrated into the GSI therapy system [2] to irradiate moving tumours with i...