This paper reviews the literature from 1977-1987 on the etiology and pathophysiology of pressure sores, factors contributing to its formation, diagnostic and pressure-measuring devices, and cushions and devices designed to prevent sores . The authors hope this review will show that many current assumptions may be invalid and should be re-examined. A pressure sore is an ulceration of the skin an...

Phenytoin (diphenlhydantion or Dilantin) is a highly effective and widely prescribed anticonvulsant agent and antiarrhythmic agent in the treatment of grand mal and psychomotor epilepsy. Phentoin was introduced into therapy in 1937 for effective convulsive disorder with a common side effect being gingival hyperplasia. In dermatology due to the stimulatory effect on the connective tissue it is u...

In the absence of infection, the pathophysiology of endotracheal tube-induced sore throat pain is unclear. Activated neutrophils release elastase, reactive oxygen species, and inflammatory cytokines known to contribute to neuropathic pain. Sterile tissue injury can cause the release of damage-associated molecular patterns such as mitochondrial DNA that promote neutrophil activation. We hypothes...

BACKGROUND Postoperative sore throat occurs frequently in surgical patients as a result of tracheal intubation. Despite advances in medical and anaesthetic care, the incidence of postoperative sore throat remains high. Our study aimed to assess the efficacy of acupuncture in the prevention of postoperative sore throat following general anaesthesia. METHODS A non-randomised clinical study (NRS...

BACKGROUND Many people with sore throat seek, and are often inappropriately prescribed, antibiotics. AIM The objective of this study was to determine the analgesic efficacy of flurbiprofen 8.75 mg microgranules versus placebo. These microgranules are a possible alternative treatment for patients with sore throat due to upper respiratory tract infection (URTI). DESIGN AND SETTING Randomised,...

on " Oriental Sore" by Captain Henry Smith, I.M.S. In the course of this article under the heading of "Treatment" he condemns " nitric acid and such agents" as "unnecessarily severe," because " they remove the sound with the diseased tissues and leave a scar larger than is necessary, a point of importance when the ulcer happens to be on the face." The treatment, however, which he recommends, na...

INTRODUCTION About 10-30% of people present to primary healthcare services with sore throat each year. The causative organisms of sore throat may be bacteria (most commonly Streptococcus) or viruses (typically rhinovirus), although it is difficult to distinguish bacterial from viral infections clinically. METHODS AND OUTCOMES We conducted a systematic review and aimed to answer the following ...

OBJECTIVES To determine whether an education and campaign program would reduce the incidence of pressure sores. MATERIAL AND METHOD The study was performed in a 1,400-bed teaching hospital in Thailand with a total number of 697patients from 47 wards for a point prevalence study; 1,201 and 1,268 patients from 12 wards to determine whether reduction of pressure sore occurrence would be obtained...

Introduction: According to the prevalence of sore mouth, its outcome and possible role of anemia in its etiology and some contradictions in this theory, our study was performed to evaluate the role of iron deficiency anemia as a etiological factor for sore mouth. Materials and Methods: This historical cohort study was performed on 40 cases, including 20 anemic patients as the experimental group...