Serum levels of adiponectin were measured in patients with benign prostatic hyperplasia and prostate cancer of pT2 and pT3 stage. Adiponectin ELISA assay, immunohistochemistry, and selected metabolic and biochemical parameters measurement was performed in 25 patients with benign prostatic hyperplasia and 43 with prostate cancer (17 patients with organ-confined and 26 patients with locally advan...

This study was conducted for qualitative analysis of serum proteins separated by SDS-PAGE and stained by Coomassie Brilliant Blue R-250 in order to describe the preliminary identification of serum proteins that may act as diagnostic marker in benign prostatic hyperplasia. Serum samples of 23 biopsy confirmed cases of benign prostatic hyperplasia and normal controls of similar age group were sub...

: Benign prostatic hyperplasia (BPH) is the overgrowth of prostate tissues with high prevalence in older men. BPH pathogenesis is not completely understood, but it is believed to be a result of de novo overgrowth of prostatic stroma. In this study, we show that aberrant activation of transforming growth factor-β (TGF-β) mobilizes mesenchymal/stromal stem cells (MSCs) in circulating blood, which...

Background. Benign prostatic hyperplasia (BPH) is a histologically determined condition of the male body and characterized by glandular-stromal multi-focal proliferation originating from paraurethral (or) transition zone prostate gland. Proliferative processes in are under control immune system. Identifying understanding immunological aspects can help tissue growth, improving men's quality life...

The management of benign prostatic hyperplasia has undergone a rapid evolution over the past decade from a surgical emphasis to a medical emphasis. Great strides in the development of alpha-adrenergic blockers, 5 alpha-reductase inhibitors and a variety of phytotherapeutics have fueled this evolution. This article reviews the past, present and future of the medical management of benign prostati...

Objectives. Dutasteride, a dual 5α-reductase inhibitor, is used to treat benign prostatic hyperplasia. Nevertheless, its histopathological effects on the morphometrics of blood vessels and glands are still controversial. The aim here was to assess the histopathological effects of dutasteride in cases of benign prostatic hyperplasia in a retrospective study. Methods. Patients with benign prostat...

results in a total of 40 sporadic prostate cancer and 80 benign prostatic hyperplasia cases, no xmrv was detected by real-time pcr and nested-pcr. rnase l r462q polymorphism analysis reveals that although there was an increase in the risk of prostate cancer correlated with the q/q allele of rnase l at position 462, the frequencies of the rnase l r462q alleles were not statistically significant ...