نتایج جستجو برای: beta subunit of human chorionic gonadotropin ßhcg

تعداد نتایج: 21328928  

Journal: :The Journal of biological chemistry 1979
Y Endo K Yamashita Y Tachibana S Tojo A Kobata

The asparagine-linked sugar chains of human chorionic gonadotropin were released from the polypeptide moiety by hydrazinolysis followed by N-acetylation and NaB3H4 reduction. More than 90% of the released radioactive oligosaccharides contained N-acetylneuraminic acid residues. After removal of N-acetylneuraminic acid residues by sialidase treatment, two neutral oligosaccharide fractions were ob...

Journal: :Antimicrobial agents and chemotherapy 2005
Giuseppantonio Maisetta Giovanna Batoni Semih Esin Giorgio Raco Daria Bottai Flavia Favilli Walter Florio Mario Campa

Bactericidal activity of human beta-defensin 3 (hBD-3) against Streptococcus mutans and Actinobacillus actinomycetemcomitans was inhibited in a dose-dependent manner by the presence of saliva and/or serum. Increasing the concentration of hBD-3 partially overcame this inhibition. A fast bactericidal effect was observed against both bacterial strains, suggesting a potential therapeutic use for hB...

Journal: :Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2010
J Cruz G Cruz R Minekawa N Maiz K H Nicolaides

OBJECTIVE To examine the effect of the duration of storage of serum and whole blood at different controlled temperatures on the concentrations of both serum free-beta-human chorionic gonadotropin (beta-hCG) and pregnancy-associated plasma protein-A (PAPP-A) in first-trimester screening for aneuploidies. METHODS The concentrations of free beta-hCG and PAPP-A were measured in samples collected ...

2015
Awatuf Elshirif Seema Sadiq

Ectopic pregnancy has been increasing in frequency over the past 2 decades. The sudden rupture of ectopic pregnancy can lead to haemorrhagic shock and death if not diagnosed and treated in a timely fashion. The first step in the diagnosis of ectopic pregnancy is demonstration of pregnancy by means of a rapidly performed and sensitive qualitative urine test for the beta-subunit of human chorioni...

Journal: :Clinical biochemistry 2004
Laurence A Cole Sarah A Khanlian

BACKGROUND False-positive hCG results can lead to erroneous diagnoses and needless chemotherapy and surgery. In the last 2 years, eight publications described cases involving false-positive hCG tests; all eight involved the AxSym test. We investigated the source of this abundance of cases and a simple fix that may be used by clinical laboratories. METHODS False-positive hCG was primarily iden...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1995
T Sugahara M R Pixley S Minami E Perlas D Ben-Menahem A J Hsueh I Boime

One of the distinguishing features of the gonadotropin and thyrotropin hormone family is their heterodimeric structure, consisting of a common alpha subunit and a hormone-specific beta subunit. Subunit assembly is vital to the function of these hormones: The conformation of the heterodimer is essential for controlling secretion, hormone-specific posttranslational modifications, and signal trans...

Journal: :Molecules 2004
Nurettin Sadikov Sahin Nasibov Cemil Oğretir Halil Berber Ali Hüseyinli

The alkylation of beta-dicarbonyl compounds in a K2CO3/DMSO system was found to afford O- and C-alkylated derivatives, depending on the type of the beta-dicarbonyl compound involved. The alkyl derivatives obtained were used in the synthesis of some new spiro barbituric acid derivatives. Quantum chemical calculations were carried out to elucidate the reaction mechanisms for some typical synthesis.

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