Learning and memory are critically dependent on basal forebrain cholinergic (BFC) neuron excitability, which is modulated profoundly by leak K(+) channels. Many neuromodulators closing leak K(+) channels have been reported, whereas their endogenous opener remained unknown. We here demonstrate that nitric oxide (NO) can be the endogenous opener of leak K(+) channels in the presumed BFC neurons. ...

The rootless duckweed Wolffia globosa, not explored toward electrogenicity till now, is investigated as a putative biocatalyst in Plant-based Biofuel Cells (P-BFC) for the electrical current generation and its basic metabolic changes during polarization are depicted. After short adaptation period, open-circuit voltage of P-BFC, utilizing W. globosa an anodic biocatalyst, reaches values 630 mV. ...

The objective of this study was to evaluate the physical and chemical properties of the broiler feather concentrate (BFC) in different hydrolysis processes. The raw materials in the form of broiler feather waste (BFW) were hydrolyzed into broiler feather concentrate (BFC) products in the form of feather meal. A total of 1000 g of dry feather samples were used in this study. The study was design...

We used a fully automated system for the behavioural measurement of physiologically meaningful properties of basic mechanisms of cognition to test two strains of heterozygous mutant mice, Bfc (batface) and L1, and their wild-type littermate controls. Both of the target genes are involved in the establishment and maintenance of synapses. We find that the Bfc heterozygotes show reduced precision ...

The primary objective of this study is to evaluate the antitussive, expectorant and anti-inflammatory effects of alkaloids imperialine (I), chuanbeinone (II), verticinone (III), and verticine (IV), which were isolated from the Bulbus Fritillariae Cirrhosae (BFC) using phytochemical method. The results showed that all the alkaloids significantly inhibited cough frequency and increased latent per...

Antonio Alonso-Ayuso1, Laureano F. Escudero2,∗ and M. Teresa Ortuño3 Escuela Sup. de Ciencias Experimentales y Tecnoloǵıa Universidad Rey Juan Carlos, Móstoles (Madrid), Spain e-mail: [email protected] Centro de Investigación Operativa Universidad Miguel Hernández, Elche, (Alicante), Spain. e-mail: [email protected] Depto. de Estad́ıstica e Investigación Operativa I Universidad Complutense de...

Cell-cell signaling is an important component of the stem cell microenvironment, affecting both differentiation and self-renewal. However, traditional cell-culture techniques do not provide precise control over cell-cell interactions, while existing cell-patterning technologies are limited when used with proliferating or motile cells. To address these limitations, we created the Bio Flip Chip (...

Estimation is still a challenging process for planning and managing software projects. Often, estimates are being done on experiential or analogous basis or using effort estimation models. Mostly, these approaches take software size (e.g., Lines of Code, Function Points, Object points) and other cost factors as the main inputs to estimation. This study focuses on functional size based effort es...

Cooperative communications are effective in improving the performance and extend the coverage of wireless networks. One issue is to find proper methods to allocate cooperative nodes. In this paper we investigate the effects of relay position and power allocation strategy in cooperative communications employing space-time codes (STCs). We consider non-ideal links between source, relay, and desti...

Recently high-speed networks have been utilized by attackers as Distributed Denial of Service (DDoS) attack infrastructure. Services on high-speed networks also have been attacked by successive waves of the DDoS attacks. How to sensitively and accurately detect the attack traffic, and quickly filter out the attack packets are still the major challenges in DDoS defense. Unfortunately most curren...