The lack of variation in antifungal drugs, and the misuse or inappropriate use usually causes resistant strains of the yeast in human’s normal flora. Unfortunately, a large number of Candida infection cases in immunosuppressed patients with insufficient treatment eventually can cause patient's death. The aim of this study was to evaluate the in vitro conventional antifungal azole compounds with...

Understanding the physical behavior of polymer-based lubricants on the nanoscale is of critical importance to a myriad of engineering applications and devices. We have used molecular dynamics simulations to quantitatively evaluate the physical mechanisms underlying perfluoropolyether lubricant spreading on a solid substrate. We quantify the effect of molecular mass, molecule length, and lubrica...

We investigated the neural processing of binary gustatory mixtures of amino acids by the facial taste system of the channel catfish, Ictalurus punctatus. In vivo electrophysiological recordings indicated that the magnitude of both integrated and single-unit facial taste responses to binary mixtures of amino acids was greatest if the components bound to independent receptor sites. Facial taste r...

This paper explains the effect of various lubricant and engine temperatures on the intake mass air flow, engine noise and lubricant pressure behaviour of a motor-driven spark ignition engine. The lubricant pressure, engine noise and mass air flow changes were recorded under a steady state operating condition with an increased engine speed in which both the volume and temperature of the lubrican...

some drugs have low bioavailability due to their poor aqueous solubility and/or slowdissolution rate in biological fluids. stiripentol (stp) is a novel anticonvulsant drug that isstructurally unrelated to the currently available antiepileptics. it has poor aqueous solubilityand its solubility has to be enhanced accordingly. polyethyleneglycol 6000 (peg-6000) iscommonly utilized as a hydrophilic...

Solubility data of refrigerant/lubricant mixtures have been modeled with a cubic equation of state. The systems studied are binary mixtures of hydrofluorocarbons (R-32, R-125, R-134a and R-143a) and alkylbenzene oils (viscosity grades 15 and 32). These partially miscible mixtures are well correlated with the present model, which can be used for calculating the pressure-temperature-composition r...