نتایج جستجو برای: biochemical genetics

تعداد نتایج: 208150  

2002
Elaine R. Radwanski

Tryptophan is the one of the least abundant yet, in terms of energy, one of the most expensive to produce of the standard protein amino acids (Hrazdina and Jensen, 1992). The Iow leve1 of soluble tryptophan present in plants (1 to 15 pM) belies the importance of the amino acid and the pathway that produces it (Gilchrist and Kosuge, 1980). Animals, and some eubacteria, lack the ability to synthe...

Journal: :The Journal of General Physiology 1948
Claude A. Villee

The metabolism of the imaginal discs of wild type, miniature, vestigial, and four-jointed varieties of Drosophila was investigated using the Cartesian diver ultramicrorespirometer. Wild type and vestigial wing disc respiration is inhibited by cyanide and azide and thus is mediated by an iron or copper porphyrin system, presumable cytochrome-cytochrome oxidase. Respiration is also inhibited by c...

Journal: :Genes & development 2006
David J Solecki Eve-Ellen Govek Toshifumi Tomoda Mary E Hatten

The diversity of neuronal morphologies and the complexity of synaptic connections in the mammalian brain provide striking examples of cell polarity. Over the past decade, the identification of the PAR (for partitioning-defective) proteins, their function in polarity in the Caenorhabditis elegans zygote, and the conservation of polarity proteins related to the PAR polarity complex in Drosophila ...

Journal: :Fungal biology 2011
Meritxell Riquelme Oded Yarden Salomon Bartnicki-Garcia Barry Bowman Ernestina Castro-Longoria Stephen J Free Andre Fleissner Michael Freitag Roger R Lew Rosa Mouriño-Pérez Michael Plamann Carolyn Rasmussen Corinna Richthammer Robert W Roberson Eddy Sanchez-Leon Stephan Seiler Michael K Watters

Neurospora crassa has been at the forefront of biological research from the early days of biochemical genetics to current progress being made in understanding gene and genetic network function. Here, we discuss recent developments in analysis of the fundamental form of fungal growth, development and proliferation -- the hypha. Understanding the establishment and maintenance of polarity, hyphal ...

2005
Colleen Witt Subhadip Raychaudhuri Arup K. Chakraborty

Immunological phenomena that were once deduced from genetic, biochemical, and in situ approaches are now being witnessed in living color, in three dimensions, and in real time. The information in time-lapse imaging can provide valuable mechanistic insight into a host of processes, from cell migration to signal transduction. What we need now are methods to quantitate these new visual data and to...

2011
Julia E. Weigand Sina R. Schmidtke Tristan J. Will Elke Duchardt-Ferner Christian Hammann Jens Wöhnert Beatrix Suess

While many different RNA aptamers have been identified that bind to a plethora of small molecules only very few are capable of acting as engineered riboswitches. Even for aptamers binding the same ligand large differences in their regulatory potential were observed. We address here the molecular basis for these differences by using a set of unrelated neomycin-binding aptamers. UV melting analys...

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