We have systematically examined the effects of chitosan film or chitosan in combination with nanometal particles (nanogold or nanosilver particles) on the growth of Schwann cells (S16) and DRG neurons (50B 11). Our results strongly suggest chitosan and chitosan in combination with nanogold particles had no effects on the growth kinetics of Schwann cells but had slightly slowed those of DRG neur...

umbilical cord blood (ucb) as a source of hematopoietic stem/progenitor cells (hspcs) used for umbilical cord blood transplantation (ucbt). the main obstacle in application of this source as an appropriate source of hspcs is low volume of this product. so ex vivo expansion of these cells in a microenvironment which mimic body condition is important. in current study we designed biocompatible mi...

Ultraviolet radiations have many detrimental effects in living organisms that challenge the stability and function of cellular structures. UV exposure also alters the properties and durability of materials and affects their lifetime. It is becoming increasingly important to develop new biocompatible and environmentally friendly materials to address these issues. Inspired by the strategy develop...

Shape morphing materials, especially those fabricated by 4D printing, are gaining much attention due to their versatility of actuation and capability being programmed in advance. These materials become particularly interesting for biomedical applications where implant could be remotely actuated, exerting a force on the surrounding tissues cells. However, this field have been restricted biocompa...

Although bone grafting has a well-recognised role in orthopaedic surgery for the treatment of nonunion, bridging diaphyseal defects and filling metaphyseal defects, it is associated with postoperative pain and morbidity. When extensive grafting is required, as in spinal arthrodesis and the management of large bony defects, inadequate amounts of autologous bone may not be available. Allograft bo...