* Corresponding author: [email protected] Abstract As part of an ongoing effort to develop computerized planning tools for cryosurgery, the current study focuses on validating a numerical technique for bioheat transfer simulations. The long-term goal is to develop a planning tool for cryosurgery that takes a 3D reconstruction of a target region, and suggests the best cryoprobe layout. To make the p...

Hyperthermia based cancer treatments are used to increase the susceptibility of cancerous tissue to subsequent radiation or chemotherapy treatments, and in the case in which a tumor exists as a well-defined region, higher intensity heat sources may be used to ablate the tissue. Utilizing the guidance of real-time treatment data while applying a laser heat source has the potential to provide unp...

This paper investigated the numerical scheme extended to solve the hyperbolic non-Fourier form of bioheat transfer equation and the experimental trials were conducted to validate the numerical simulation. MNPs were prepared via co-precipitation and modified with a silica layer. The amino modified Fe3O4/SiO2 nanoshells were covered with gold colloids producing nanoshells of Fe3O4/SiO2/Au (MNSs)....

In this work, numerical estimations of a nonlinear hyperbolic bioheat equation under various boundary conditions for medicinal treatments tumor cells are constructed. The heating source components in transfer model, such as the rate blood perfusions and metabolic generations, considered experimentally temperature-dependent functions. Due to nonlinearity governing relations, finite element metho...

This paper presents a hybrid finite element model for describing quantitatively the thermal responses of skin tissue under laser irradiation. The model is based on the boundary integral-based finite element method and the Pennes bioheat transfer equation. In this study, temporal discretization of the bioheat system is first performed and leads to the well-known modified Helmholtz equation. A ra...

Accurate treatment planning is necessary for the successful application of hyperthermia in the clinic. The validity of four different bioheat models or combinations of models is evaluated: the conventional bioheat transfer equation, the limited effective conductivity model, a mixed heat sink-effective conductivity model and a discrete vessel model. The heat balance for the heated volume, and es...

The principal objective of this work was to develop a semi-implicit hybrid boundary element method (HBEM) describe the nonlinear fractional biomechanical interactions in functionally graded anisotropic (FGA) soft tissues. local radial basis function collocation (LRBFCM) and general (GBEM) were used solve dual-phase-lag bioheat governing equation. (BEM) then poroelastic To equations arising from...

BACKGROUND Peritoneal carcinomatosis occurs in different cancer subtypes and is associated with a dismal prognosis. Some doubts remain whether the whole abdomen can be treated by regional hyperthermia, therefore we analyzed feasibility conducting a pilot study. METHODS A simulation of the abdominopelvic heat distribution in 11 patients with peritoneal carcinomatosis was done using the HyperPl...