BACKGROUND Rhazya stricta Decne. is a medicinal plant that is widespread in Saudi Arabia and desert areas of the Arabian Peninsula. Its extract contains alkaloids, tannins, and flavonoids that are involved in different biological activities. The study aim was to evaluate the effects of Rhazya stricta plant extracts on the proliferation and differentiation of NTERA-2 (NT2) pluripotent embryonal ...

Human peripheral blood lymphocytes (PBLs) produce metallothioneins (MTs) in response to a variety of heavy metal ions. MTs could therefore be a candidate for a marker that represents the biological effect of heavy metals. Since it is practically difficult to measure MT protein levels in PBLs, we examined if MT-mRNA could serve as a biomarker of heavy metal exposure. It is difficult to obtain RN...

It was perhaps fitting that Lieut.-Colonel Edward Lawrie, should signalise the year of his retirement from the post of R,esidenc\r Surgeon at Hyderabad by the publication of a volume on Chloroform, a subject with which he has been identified for many years past, and in defence of his views on which, and those of his master Syme, he has fought non sine gloria for many }7ears. The introduction to...

background and objectives: datura innoxiamilleris one of the two species of datura (solanaceae) which grow in iran. there are many reports of the biological activities of datura and in the present study the ability of datura innoxia for inhibiting angiogenesis was evaluated. methods: the methanol extract and petroleum ether, chloroform and methanol fractions of datura innoxia flowers were obtai...

BACKGROUND/AIM Alzheimer disease (AD) is triggered by interactions of multiple genetic and environmental factors. The APOE gene E4 allele is the best-known risk factor for AD, yet it represents a small ratio of genetic factors. According to genome-wide association studies, the BIN1 gene is the second important risk factor for AD, following the APOE gene. We aimed to identify a novel biomarker i...

The Bignoniaceae family has 110 genera and approximately 650 species, widely distributed in tropical regions. Among the genera of this family, the Adenocalymma (46 species) have been little investigated from a phytochemical point of view, found only ethnobotanical reports. The aim of this study was the phytochemical characterization of chloroform, dichlorometane and ethyl acetate extracts from ...

Following the introduction by Duncombe of a colorimetric micromethod for the determination of free fatty acids (FFA) dissolved in chloroform, we studied the optimum conditions for chloroform extraction of FFA from blood or other biological fluids. A degree and rate of extraction similar to those with Dole’s extraction mixture were obtained. Phospholipids are not extracted by the procedure descr...

Herbal medicines possess a great demand in both developed and developing countries as a source of primary health care owing to their attributes having wide biological and medicinal activities, high safety margins and lesser costs. People living in rural areas of Nepal depend largely in the herbal medicines for the treatment. The present study concerns with the study of pharmacognostic character...