Hydrogels are of great interest in the field of biosensing for their good biocompatibility, plasticity, and capability of providing 3D scaffolds. Nevertheless, the application of hydrogels has not been linked with broad surface biosensing systems yet. To overcome the limitations, here for the first time, surface-immobilized pure DNA hydrogels were synthesized using a surficial primer-induced st...

A novel multiparametric biosensor system based on living cells will be presented. The biosensor system includes two biosensing techniques on a single device: resonant frequency measurements and electric cell-substrate impedance sensing (ECIS). The multiparametric sensor system is based on the innovative use of the upper electrode of a quartz crystal microbalance (QCM) resonator as working elect...

We review progress toward microcantilever arrays with in-plane photonic readout for biosensing applications. Microcantilever arrays are fabricated on individual silicon-on-insulator (SOI) chips and integrated with two-layer polydimethylsiloxane (PDMS) microfluidics that incorporate fluid channels and valves. Microcantilever functionalization is accomplished by inkjetting appropriate fluids onto...

In this work, a novel photoelectrochemical biosensing strategy was designed for cell assay under 630 nm (red light) excitation. WS2/Au NP nanocomposites were prepared as a photoelectrochemical biosensing substrate. The localized surface plasmon resonance effect of Au NPs tremendously improved the photoelectric conversion efficiency and enhanced the detection sensitivity.

DNA methylation has the potential to be a clinically important biomarker in cancer. This communication reports a real-time and label-free biosensing strategy for DNA methylation detection in the cancer cell line. This has been achieved by using surface plasmon resonance biosensing combined with the highly specific molecular inversion probe based amplification method, which requires only 50 ng o...

Research in biosensing currently occupies an important role among biomolecular detection techniques, especially with respect to medical diagnoses. Is this sense, the development of biosensors based on localized surface plasmon resonance (an optical transducer) or electrochemical transductions have been highlighted. However, and working together enable more versatile detections biosensing. Thus,...

This review focusses on the supramolecular interactions between metal–organic frameworks (MOFs) and included biomolecules. Examples demonstrating utility of crystallography, spectroscopic techniques, computational modelling for probing such are highlighted. Key papers illustrating importance intraframework to structure, flexibility, availability functional groups in bioMOFs also discussed. Fina...

Scientific research in plasmonic metasurfaces has been widely widespread the last years, motivated by recent advances nanofabrication field and increasing demand for high throughput sensing platforms. The electronics, microfluidics, signal processing have enabled complete development of highly integrated devices with broad application potential. However, progress observed from a fabrication poi...