Whereas many healthy people consider their bleeding and bruising excessive, patients with underlying von Willebrand disease, the most common hereditary bleeding disorder, often fail to identify their bleeding symptoms. Therefore, it is necessary to ask for specific information from patients about bleeding and bruising (Is the patient easily bruised? What is the size of the bruises? If the patie...

Hemophilia type A is a rare inherited bleeding disorder with a diversity of clinical manifestations ranging from persistent bleeding after minor trauma, spontaneous deep muscle or joint hemorrhage, to intracranial hemorrhage. As an X-linked disorder, hemophilia is rare in females and therefore there is little experience with pregnancy and no standardized guidelines to prevent bleeding antepartu...

Background Hemostatic disorder and massive bleeding are common complications after cardiac surgery procedures, particularly in procedures requiring prolonged cardiopulmonary bypass. Conventional laboratory coagulation tests failed to predict hemostatic disorder and consequent proclivity to excessive bleeding. On the other hand there is evergrowing proportion of patients who need antiplatelet th...

In liver disorder, prothrombin time (PT) is elevated, and fibrinogen level decreased which are considered predictors of increased bleeding risk. We aimed at determining whether increased PT and fibrinogen value reflect the haemostatic potential and bleeding risk in patients with liver disorder. The study comprises a total of 135 subjects including patients with liver disorder (n=75) and healthy...

Acquired haemophilia A is a serious and potentially fatal bleeding disorder. Diagnosis is difficult and maybe delayed due to its rarity. The high mortality rate and the complex nature of treatment necessitate patient management at a and resources are available. Prompt diagnosis is crucial and early initiation of therapy could be life saving. Management includes initial control of bleeding follo...

Bleeding symptoms are frequently reported even in otherwise healthy subjects, and differentiating a normal subject from a patient with a mild bleeding disorder (MBD) can be extremely challenging. The concept of bleeding rate, that is, the number of bleeding episodes occurring within a definite time, could be used as the unifying framework reconciling the bleeding risk observed in congenital and...

BACKGROUND Approximately 1% of U.S. women may have an undiagnosed bleeding disorder, which can diminish quality of life and lead to life-threatening complications during menstruation, childbirth, and surgery. PURPOSE To understand young women's knowledge, attitudes, and perceptions about bleeding disorders and determine the preferred messaging strategy (e.g., gain- versus loss-framed messages...