Twelve dentulous patients, age 65 or older, with no medical or pharmacologic predisposition to gingival hyperplasia were enrolled in a controlled clinical trial to evaluate the effect of the unaided use of an ultrasonic toothbrush on supragingival plaque and gingival bleeding. Subjects used the ultrasonic toothbrush in lieu of their conventional toothbrushes for a 30-day period. Clinical measur...

Introduction: Smoking is a known risk factor of periodontitis. Cotinine, a metabolic by product of nicotine is involved in the pathogenesis of periodontitis. Changes in gingival microvasculature, gingival epithelium take place which manifest clinically as decreased bleeding on probing and reduced inflammatory response, increased gingival thickness etc. Knowing the importance of gingival thickne...

BACKGROUND Selective serotonin reuptake inhibitors (SSRIs) have been associated with upper gastrointestinal (GI) bleeding. Given their worldwide use, even small risks account for a large number of cases. This study has been conducted with carefully collected information to further investigate the relationship between SSRIs and upper GI bleeding. METHODS We conducted a case-control study in ho...

INTRODUCTION Inherited defects in RUNX1 are important causes of platelet function disorders. AIM Our goals were to evaluate RUNX1-related platelet disorders among individuals evaluated for uncharacterized, inherited platelet function disorders and test a proof of concept that bleeding risks could be quantitatively estimated for typical families with an inherited platelet function disorder. ...

Aim To evaluate the effectiveness on tissue response of the new nutritional supplement made of oligomeric proanthocyanidins in induced gingivitis after 21 days of use. Material and Methods A prospective, double-blind, randomized, controlled clinical trial was carried out on 20 patients; it is divided into an experimental group and a control group after fulfilling the selection criteria. Patie...

Background The poor hygiene of peri-implant tissues causes inflammation at tissue-implant interface, which may impair the rehabilitation success. The aim of this study was to evaluate the influence of external hexagon and Morse taper implants on peri-implant health in patients wearing mandibular overdentures for 1 year. Materials and Methods A total of 46 implants were evaluated, 28 external ...

background: chlorhexidine (chx) as a gold standard chemical agent appears to be the most effective antimicrobial agent for reduction of both plaque and gingivitis. the aim of this study was to compare the efficacy of two concentrations of digluconate chlorhexidine (chx) solutions (0.12% and 0.20%) on gingival indices and the level of dental staining during 14 days. materials and methods: in thi...

background: recently, there has been interest in non‑mammalian collagen sources such as fish collagen in the development of biomatrices and scaffolds for periodontal regeneration. in the present study, a novel collagen barrier membrane of fish origin was assessed in the treatment ofperiodontal intra‑bony defects. materials and methods: ten systemically healthy chronic periodontitis patients hav...

BACKGROUND Bleeding among patients with acute myocardial infarction (AMI) is associated with worse long-term outcomes. Although the mechanism underlying this association is unclear, a potential explanation is that withholding antiplatelet therapies long beyond resolution of the bleeding event may contribute to recurrent events. METHODS AND RESULTS We examined medication use at discharge, 1, 6...