AIM To study effects of a perfluorocarbon emulsion on plasma and whole human blood viscosity in the presence of albumin or modified fluid gelatin. MATERIAL AND METHODS We investigated the effects of several PFC concentrations on plasma and whole blood viscosity in the presence of human albumin solution (HAS) or modified fluid gelatine (MFG; Gelofusine) to obtain three PFC emulsion concentrati...

It is well known that massage therapists often develop a number of health problems relatively early on in their career. A preliminary study showed that grounding massage therapists during their work may alleviate some of the health problems they encounter. A doubled-blind randomized controlled trial was designed to examine the effects of working and sleeping grounded for 4 weeks on massage ther...

We studied the effect of a synthetic copolymer surfactant, poloxamer 188, on cerebral blood flow in a rabbit model of focal cerebral ischemia. Following retro-orbital craniectomy, the parietal branch of the middle cerebral artery was occluded with bipolar current. Cerebral blood flow was measured by the hydrogen clearance technique using platinum-iridium electrodes placed within the parietal co...

We investigated several rheologic variables in 17 patients (11 men, six women, mean age = 52. 1 + 9.8 years) with chronic stable angina. None took any medication except for sublingual nitroglycerin for 2 weeks before the study, and all had angiographically proven coronary artery disease with no history of myocardial infarction. Rheologic measurements included hematocrit, whole blood and plasma ...

Some haematological and rheological features were compared in 27 age and sex matched pairs of patients (15 male, 12 female) with homozygous sickle cell (SS) disease with and without proliferative sickle retinopathy (PSR). Significant haematological differences between the groups were a higher haemoglobin and a lower fetal haemoglobin in PSR positive males and a higher MCHC in PSR positive femal...

Objective To investigate the role of whole blood viscosity in digital ulcer (DU) development in patients with diffuse and limited Systemic sclerosis. Methods A convenience sample of patients with Systemic sclerosis (SSc) was selected from the adult Rheumatology clinic at the University of Chicago. The study group consisted of patients with SSc (with ulcers present, a history of ulcers, and no...

The effect of transfusing a nonextravasating, zero-link polymer of cell-free hemoglobin on pial arteriolar diameter, cerebral blood flow (CBF), and O2 transport (CBF x arterial O2 content) was compared with that of transfusing an albumin solution at equivalent reductions in hematocrit (approximately 19%) in anesthetized cats. The influence of viscosity was assessed by coinfusion of a high-visco...

Repeat low density lipoprotein (LDL) apheresis and blood flow determinations in the forearm and leg were performed in 10 patients (age range, 13-49 years; four male, six female) with familial hypercholesterolemia (eight homozygous, two heterozygous). To perform LDL apheresis, plasma was first separated by a polysulphone hollow fiber filter; then, LDL was selectively removed from plasma by dextr...

In an interesting study, Jung et al.1) found an effective reduction of whole blood viscosity in statin naïve acute coronary syndrome (ACS) patients with early statin administration. In statin naïve ACS patients they found an apparent decrease in whole blood viscosities at both of the two shear rates. The hypothesis that a lipid-lowering reagent, statin, contributes to blood viscosity decrease i...