To the Editor: Until a few years ago, the most frequent microbiologi-cally documented cause of severe bloodstream infections among patients with hematologic malignancies was gram-positive bacteria (1). However , over the years, gram-negative bacteria have become the main infectious cause of death among patients with hematologic malignancies, and rates of different phenotypes associated with ant...

OBJECTIVES To determine the efficacy of oral amphotericin B for the prevention of Candida bloodstream infection in the pediatric intensive care unit. DESIGN Retrospective, nonrandomized, historic-control study. SETTING Multidisciplinary pediatric intensive care unit at a university-affiliated children's medical center. PATIENTS Study group included all patients admitted to the pediatric i...

bloodstream infections with salmonella typhi, is uncommon in human immunodeficiency virus (hiv)-infected persons. the symptoms in such patients are often non-specific and have a rather insidious onset and progression. we report a patient with sepsis and lower limb gangrene due to salmonella typhi infection in an hiv-infected patient.

Catheter-related bloodstream infection is one of the most serious complications of central venous access devices. Antimicrobial-coated catheters represent one novel strategy to prevent catheter-related bloodstream infection. A comprehensive economic evaluation is essential to guide informed decision-making regarding the adoption of this technology and its expected benefits in healthcare institu...

Background Bloodstream Infection and Central Line-Associated Bloodstream Infection (BSI/CLABSI) in Intensive Care Units (ICUs) are associated with clinical and economic burden. Chlorhexidine gluconate body washing with washcloths (CHG-WC) has been described as potentially effective towards reducing the spread of infection. Current systematized evidence has not fully ascertained the impact of CH...

OBJECTIVE Determine the impact of three stepwise interventions on the rate of central catheter-associated bloodstream infections. DESIGN Quasi-experimental study. SETTING Three surgical intensive care units (general surgery, trauma, and neurosurgery) at a 1500-bed county teaching hospital in the Miami metro area. PATIENTS All consecutive central catheter-associated bloodstream infection c...

OBJECTIVES Hospital-acquired bloodstream infections are known to increase the risk of death and prolong hospital stay, but precise estimates of these two important outcomes from well-designed studies are rare, particularly for non-intensive care unit (ICU) patients. We aimed to calculate accurate estimates, which are vital for estimating the economic costs of hospital-acquired bloodstream infec...