OBJECTIVE To develop a system to score disease activity based on clinical manifestations in patients with active ulcerative colitis and to assess the relationship of this score with endoscopic disease severity as assessed by colonoscopy. METHODS In a pilot study of 43 patients, nine clinical variables were examined by univariate analysis. Six factors that correlated with disease severity incl...

PURPOSE The clinical presentations of inflammatory bowel disease (IBD) prior to diagnosis are so diverse or vague that many of them waste time before final diagnosis. This study was undertaken to know the medical history of the pediatric patients until the final diagnosis could be reached. METHODS The medical records of all pediatric patients who were diagnosed with IBD (Crohn's disease [CD] ...

Background: Necrotizing enterocolitis is one of the serious complications of prematurity. Eosinophilia has not been proposed as a classical laboratory abnormality in NEC. Previous studies suggest that eosinophilia during NEC may be a sign of allergic enterocolitis. Case presentation: We present a premature neonate with birth weight of 1280 grams with abdominal distention, bilious gastric resid...

AIM To investigate whether children with autistic spectrum disorder (ASD) have bowel symptoms consistent with underlying enterocolitis. METHODS Information on children's stool patterns and gut symptoms collected by questionnaire at 4 weeks and at 6, 18, 30 and 42 months of age were available for 12,984 children from the Avon Longitudinal Study of Parents and Children (ALSPAC). Data on the 78 ...

Common marmosets (Callithrix jacchus) are frequently used for biomedical research but can be afflicted with diarrhea-a serious and potentially lethal health problem. Enteropathogenic Escherichia coli (EPEC) is thought to be the causative pathogen of hemorrhagic typhlocolitis in common marmosets, but the actual incidence of the disease and the relationship between EPEC and hematochezia are unkno...

Purpose: To study the effect of interaction between methanol leaf extract of Spondias mombin and amoxicillin on diarrheagenic Escherichia coli (DEC). Methods: Cold methanol extraction of Spondias mombin leaf and its phytochemical screening were carried out. Isolated, characterized and identified strains of enterotoxigenic E. coli (ETEC), enteroinvasive E. coli (EIEC), and enterohemorrhagic E. c...

INTRODUCTION Norovirus infection with necrotizing enterocolitis has so far been reported as a specific tropism of the small bowel in premature newborns. CASE PRESENTATION Three cases of premature newborns presenting with extensive isolated colonic ischemia due to norovirus infection are reported.Patient 1 was a Caucasian girl with a gestational age of 29+2 weeks. She had sudden onset of abdom...

We present a case of a 36-year-old female patient who was initially admitted to the Department of Infectious Diseases for evaluation of diarrhea. Two years prior to admission, she had been treated in another hospital for erythema nodosum on her calves. There was no further diagnosis at that time. The patient presented with frequent loose stool for three weeks before admission to our Department,...

The research included the isolation of 12 bacterial isolates from stool samples children with acute watery and bloody diarrhea under age five years, as it was possible to obtain 6 Escherichia coli, 3 Salmonella typhimurium, Shigella flexneri. Vitek2 system, inhibitory activity lactoferrin killer toxin produced S. cerevisiae against pathogenic bacteria studied by well diffusion method, results r...