Rheumatoid arthritis (RA) is a systemic autoimmune disease with chronic inflammatory process that negatively affects bone metabolism, leading to violation of mineral density (BMD). Bone remodeling markers are important indicators the state tissue can provide additional information for clinician about BMD disorders. The patients were randomly enrolled in study preliminary stratification by prese...

OBJECTIVE To investigate factors associated with bone mineral density (BMD) in type 1 diabetes by classic statistic and artificial neural networks. RESEARCH DESIGN AND METHODS A total of 175 eugonadal type 1 diabetic patients (age 32.8 ± 8.4 years) and 151 age- and BMI-matched control subjects (age 32.6 ± 4.5 years) were studied. In all subjects, BMI and BMD (as Z score) at the lumbar spine (...

BACKGROUND Although dual energy X-ray absorptiometry (DXA) is known to standard equipment for bone mineral density (BMD) measurements. Different results of BMD measurement using a number of different types of devices are difficult to use clinical practice. The purpose of this study was to evaluate discrepancy and standardizations of DXA devices from three manufactures using a European Spine Pha...

This study investigated whether or not vitamin D and calcium supplementation affected bone metabolism and bone mineral density (BMD) over a period of four years of denosumab therapy in patients with primary osteoporosis. Patients were divided into a denosumab monotherapy group (22 cases) or a denosumab plus vitamin D and calcium supplementation group (combination group, 21 cases). We measured s...

Bone mineral density (BMD) is one of the quantitative traits that are genetically inherited and affected by various factors. Over the past years, genome-wide association studies (GWASs) have searched for many genetic loci that influence BMD. A recent meta-analysis of 17 GWASs for BMD of the femoral neck and lumbar spine is the largest GWAS for BMD to date and offers 64 single-nucleotide polymor...

METHODS AND RESULTS Seventy Lebanese men (aged 65-84 years) participated in this study. Body weight and height were measured and body mass index (BMI) was calculated. Body composition (lean mass, fat mass and fat mass percentage) was assessed by dual-energy X-ray absorptiometry (DXA). Bone mineral content (BMC) of whole body (WB) and BMD of WB, total hip (TH), femoral neck (FN), ultra distal (U...

Our objective was to estimate the relationship between longitudinal change in BMD and fragility fractures. We studied 3635 women and 1417 men 50-85 yr of age in the Canadian Multicentre Osteoporosis Study who had at least two BMD measurements (lumbar spine, femoral neck, total hip, and trochanter) within the first 5 yr of the study and fragility fractures (any, main, forearm/wrist, ribs, hip) w...

A few studies have investigated the relationship between type 1 diabetes mellitus (T1DM) and bone mineral density (BMD) values. This meta-analysis was performed to explore differences between T1DM and healthy individuals in BMD values measured at five bone sites.We searched the database of PubMed for cross-sectional studies about the association of T1DM and BMD, and a meta-analysis was conducte...

In order to observe and compare the changes of bone mineral density (BMD) paraplegic patients before after wearing walking device, as well influence age, height, weight years on BMD, 124 were tested by quantitative CT (QCT) in Sichuan Rehabilitation Hospital (Sichuan Bayi Center). The results showed that walkers had higher than those not walkers. BMD decreased with but significantly non-paraple...