there is no randomized study carried out in order to compare their pharmacokinetic parameters although midazolam, as a sedative, has been widely administered via continuous infusion as well as intermittent bolus doses in mechanically ventilated critically ill patients. we prospectively investigated the effect of these two principal methods on pharmacokinetic parameters in 23 of mentioned patien...

conclusion the designed split-bolus mdct technique can be proposed alternatively to triphasic mdct and in a single-pass to pvp in the initial staging and in the follow-up respectively in oncologic patients. patients and methods we retrospectively analyzed the follow-up split-bolus 64-detector row ct protocol in 36 oncologic patients to characterize focal liver lesions. the split-bolus mdct prot...

the objective of the present study was to investigate the effects of a sustained-release multi-trace element ruminal bolus on sex ratio, the reproductive performance and lambs growth of afshari ewes. eighty afshari cycling ewes during breeding season were used in the trial. the animals were synchronized using cidr for 14 days and assigned into 4 groups including: group 1 (n=20) received a singl...

published data on the effects of ruminal bolus on the number of ovulatory follicles in ewes does not exist. the present study determined the effects of a ruminal bolus on trace element status, follicular dynamics and reproductive performance in ewes. eighty afshari cycling ewes were synchronized during breeding season using cidr for 14 days and assigned to 4 groups (n=20); group 1 received a si...

OBJECTIVE This study was designed to investigate the effect of administration of warmed contrast material (CM) on the bolus geometry and enhancement as depicted on coronary CT angiography. MATERIALS AND METHODS A total of 64 patients (42 men, 22 women; mean age, 56 years) were randomly divided into two groups. Group 1 included 32 patients administered CM (Omnipaque [Iohexol] 350 mg I/ mL; Nyc...

AIM To assess in standard clinical practice the feasibility, efficacy, and safety of switching patients with long-standing type 2 diabetes (T2DM) and poor or unstable blood glucose control to basal-bolus insulin therapy. MATERIAL AND METHODS This was a prospective, single center study including 37 patients with T2DM (age 65±8 years, 62.2% men, body mass index 28.8±6.2 kg/m2, diabetes duration...

A shortcut review was carried out to establish whether intravenous glucagon is a safe and effective treatment for patients with suspected lower oesophageal food bolus impaction. Seven studies were directly relevant to the question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. The cl...